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Table 4 Treatment-emergent adverse events in ≥3% of mITT subjects
| Adverse Event | Tigecycline | Comparator | ||
|---|---|---|---|---|
| N = 268 | N = 263 | |||
| n (%) | n (%) | |||
| Nausea* | 117 | (43.7) | 44 | (16.7) |
| Vomiting* | 64 | (23.9) | 14 | (5.3) |
| Diarrhea* | 39 | (14.6) | 14 | (5.3) |
| Constipation | 17 | (6.3) | 22 | (8.4) |
| Dyspepsia | 17 | (6.3) | 7 | (2.7) |
| Headache | 20 | (7.5) | 22 | (8.4) |
| Pain† | 15 | (5.6) | 18 | (6.8) |
| Abdominal pain | 17 | (6.3) | 7 | (2.7) |
| Fever | 9 | (3.4) | 6 | (2.3) |
| Chest pain | 6 | (2.2) | 8 | (3.0) |
| Insomnia | 22 | (8.2) | 17 | (6.5) |
| Anxiety | 9 | (3.4) | 7 | (2.7) |
| Dizziness | 9 | (3.4) | 6 | (2.3) |
| Hypokalemia* | 6 | (2.2) | 17 | (6.5) |
| Pruritis | 15 | (5.6) | 16 | (6.1) |
| Hypertension | 8 | (3.0) | 9 | (3.4) |
| Anemia | 8 | (3.0) | 7 | (2.7) |
