Skip to main content

Table 3 Clinical cure rate at the isolate level: selected baseline isolates at test-of-cure visit (ME population)*

From: A randomized trial of tigecycline versus ampicillin-sulbactam or amoxicillin-clavulanate for the treatment of complicated skin and skin structure infections

Isolate

Tigecycline

Comparator

 

n/N

%

n/N

%

Staphylococcus aureus

54/71

76.1

49/61

80.3

 MRSA

25/36

69.4

21/29

72.4

 CA-MRSA

17/25

68.0

17/23

73.9

 MSSA

29/35

82.9

28/32

87.5

Streptococcus spp.

30/36

83.3

15/25

60.0

S. pyogenes

8/11

72.7

5/5

100

S. agalactiae

9/9

100

3/6

50.0

S. anginosus groupa

8/9

88.9

3/8

37.5

Enterobacter cloacae

5/8

62.5

1/1

100

Enterococcus spp. b

5/7

71.4

6/6

100

Escherichia coli

10/13

76.9

7/8

87.5

Klebsiella pneumoniae

5/5

100

5/6

83.2

Proteus spp. c

4/7

57.1

2/2

100

Pseudomonas aeruginosa

5/7

71.4

2/2

100

  1. *No statistically significant differences between groups. ME, microbiologically evaluable; MRSA, methicillin-resistant Staphylococcus aureus; CA-MRSA, community-acquired MRSA; MSSA, methicillin-susceptible Staphylococcus aureus. a Streptococcus anginosis, Streptococcus intermedius, Streptococcus constellatus; b Enterococcus faecalis, Enterococcus faecium; c Proteus mirabilis, Proteus penneri, Proteus vulgaris group.