Table 4 Multivariable Cox model fit: relative hazards of adverse events, with two different antiretroviral therapy encodings (n=1,096)

calendar year (per more recent)

1.01

0.96

1.07

gender M vs. F

0.52

0.38

0.71

age per one year older

1.04

1.02

1.05

nationality non-Italian vs. Italian

0.82

0.57

1.17

nationality unknown vs. Italian

1.08

0.62

1.87

risk homo/bisexual vs. heterosexual

2.03

1.40

2.94

risk IDU vs heterosexual

1.16

0.75

1.79

risk other/unknown vs. heterosexual

0.74

0.52

1.07

years from first positive test

0.99

0.96

1.02

CDC stage B vs. A

1.10

0.79

1.54

CDC stage C vs. A

1.57

1.14

2.15

HBsAg positive vs. negative

1.67

1.04

2.69

HBsAg unknown vs. negative

1.11

0.54

2.28

HCVAb positive vs. negative

1.02

0.69

1.52

HCVAb unknown vs. negative

0.68

0.34

1.36

CD4+ per cell/mm³ higher

1.00

1.00

1.00

HIV-RNA per Log₁₀ higher

0.85

0.68

1.07

subtype 17 BF vs. B

1.49

0.81

2.75

subtype 28 BF vs. B

0.96

0.56

1.65

subtype 29 BF vs. B

0.90

0.38

2.15

subtype C vs. B

1.87

0.83

4.18

subtype F1 vs. B

1.89

0.94

3.83

subtype other vs. B

1.46

0.75

2.86

subtype unknown vs. B

0.95

0.70

1.29

bilirubin high vs. normal

1.02

0.46

2.26

bilirubin unknown vs. normal

0.67

0.42

1.06

hemoglobin normal vs. low

0.97

0.66

1.40

hemoglobin unknown vs. low

0.91

0.47

1.78

gammaGT high vs. normal

0.93

0.62

1.39

gammaGT unknown vs. normal

1.12

0.77

1.64

glucose diabetes vs. normal

1.55

0.80

3.01

glucose high vs. normal

1.73

0.92

3.26

glucose unknown vs. normal

1.04

0.55

1.96

GPT high vs. normal

1.20

0.87

1.66

GPT unknown vs. normal

0.70

0.37

1.32

HDL normal vs. low

1.04

0.60

1.81

HDL unknown vs. low

0.97

0.35

2.67

LDL high vs. normal

1.51

0.56

4.03

LDL unknown vs. normal

1.62

0.58

4.51

TGL high vs. normal

0.95

0.63

1.42

TGL unknown vs. normal

1.65

1.11

2.44

MDRD normal vs. low

1.41

0.58

3.41

MDRD unknown vs. low

1.94

0.69

5.45

anti-HCV therapy

0.73

0.22

2.41

anti-TB therapy

0.93

0.63

1.37

anti-PCP therapy

0.93

0.68

1.27

other antibiotic therapy

0.99

0.71

1.37

other concomitant drugs

0.76

0.56

1.03

Atripla® vs. Truvada®+Sustiva®

0.99

0.12

8.44

Reyataz® vs. Truvada®+Sustiva®

0.27

0.03

2.27

Kaletra® vs. Truvada®+Sustiva®

1.26

0.53

2.96

any other therapy vs. Truvada®+Sustiva®

1.11

0.39

3.20

any other NRTI+NNRTI vs. Truvada®+Sustiva®

1.56

0.64

3.83

any other NRTI+PI vs. Truvada®+Sustiva®

1.59

0.62

4.04

any other NRTI+PI/r vs. Truvada®+Sustiva®

3.89

1.38

10.95

Emtricitabine* (in the cART, yes vs. no)

1.19

0.46

3.07

Lamivudine* (in the cART, yes vs. no)

1.21

0.70

2.09

Abacavir* (in the cART, yes vs. no)

2.33

0.93

5.87

Zidovudine* (in the cART, yes vs. no)

3.51

1.34

9.18

Stavudine* (in the cART, yes vs. no)

2.84

1.06

7.60

Zalcitabine* (in the cART, yes vs. no)

3.47

1.29

9.34

Didanosine* (in the cART, yes vs. no)

2.27

1.29

3.98

Tenofovir* (in the cART, yes vs. no)

2.00

0.65

6.20

Nevirapine* (in the cART, yes vs. no)

1.42

0.67

2.98

Efavirenz* (in the cART, yes vs. no)

2.40

1.14

5.03

Atazanavir* (in the cART, yes vs. no)

0.15

0.02

1.34

Fosamprenavir* (in the cART, yes vs. no)

2.77

0.76

10.09

Indinavir* (in the cART, yes vs. no)

1.76

1.04

3.00

Lopinavir* (in the cART, yes vs. no)

0.55

0.23

1.33

Nelfinavir* (in the cART, yes vs. no)

1.37

0.66

2.86

Ritonavit full dose* (in the cART, yes vs. no)

2.76

1.39

5.52

Saquinavir* (in the cART, yes vs. no)

1.75

0.91

3.36

Ritonavir boosting dose* (in the cART, yes vs. no)

1.19

0.41

3.44