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Table 6 Significant clinical variables in the bivariate analysis of patients with respect to mortality, [n (%)] except where indicated

From: Repeated Aspergillusisolation in respiratory samples from non-immunocompromised patients not selected based on clinical diagnoses: colonisation or infection?

 

Total patients (n = 245)

Colonised (n = 106)

Aspergillosis (n = 139)

 

Died (n = 76)

Survived (n = 169)

p

Died (n = 13)

Survived (n = 93)

p

Died (n = 63)

Survived (n = 76)

p

Days to isolation (X ± SD)

13.0 ± 14.2

9.2 ± 8.5

0.012

6.5 ± 8.5

7.7 ± 6.3

0.126

14.3 ± 14.8

10.8 ± 10.2

0.153

Smokers

17 (22.4)

21 (12.4)

0.047

2 (15.4)

12 (12.9)

0.805

15 (23.8)

9 (11.8)

0.063

COPD

49 (64.5)

124 (73.4)

0.158

8 (61.5)

65 (69.9)

0.549

41 (65.1)

59 (77.6)

0.101

Malignancies

21 (27.6)

17 (10.1)

0.001

4 (30.8)

6 (6.5)

0.015

17 (27.0)

11 (14.5)

0.089

Charlson (X ± SD)

3.20 ± 2.64

2.34 ± 1.85

0.012

4.1 ± 3.2

2.2 ± 1.7

0.019

3.0 ± 2.5

2.5 ± 2.0

0.376

McCabe (Non fatal)

33 (43.4)

114 (67.5)

0.001

2 (15.4)

63 (67.7)

0.001

31 (49.2)

51 (67.1)

0.032

APACHE II (X ± SD)

16.3 ± 7.7

11.7 ± 5.9

0.001

14.0 ± 7.9

11.3 ± 5.8

0.191

16.8 ± 7.6

12.3 ± 6.1

0.001

ICU admission

32 (42.1)

26 (15.4)

0.001

4 (30.8)

11 (11.8)

0.086

28 (44.4)

15 (19.7)

0.002

ICU stay (days; X ± SD)

6.9 ± 7.6

6.8 ± 7.6

0.937

1.9 ± 5.8

0.7 ± 2.5

0.167

2.9 ± 6.0

1.5 ± 4.9

0.017

Dyspnoea

59 (77.6)

114 (67.5)

0.106

6 (46.2)

60 (64.5)

0.201

53 (84.1)

54 (71.1)

0.068

Infiltrates (X-ray / CT)

59 (77.6)

90 (53.3)

0.001

7 (53.8)

42 (45.3)

0.570

52 (82.5)

48 (63.2)

0.011

Cavitations (X-ray / CT)

19 (25.0)

19 (11.2)

0.006

1 (7.7)

4 (4.3)

0.487

18 (28.6)

15 (19.7)

0.237

Worsening X-ray signs

40 (52.6)

18 (10.7)

0.001

4 (30.8)

3 (3.3)

0.002

36 (57.1)

15 (19.7)

0.001

Steroids prior to admission

43 (56.6)

58 (34.3)

0.001

4 (30.8)

25 (26.9)

0.748

39 (61.9)

33 (43.4)

0.030

Steroids during admission

68 (89.5)

117 (69.2)

0.001

11 (84.6)

63 (67.7)

0.336

57 (90.5)

54 (71.1)

0.004

Antifungal treatment

60 (78.9)

81 (47.9)

0.001

7 (53.8)

24 (25.8)

0.052

53 (84.1)

57 (75.0)

0.187