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Table 5 Univariate and multivariate analysis of the association of maternal characteristics with death among neonates*

From: Clinical features and risk factors for severe and critical pregnant women with 2009 pandemic H1N1 influenza infection in China

Variables Neonates who survived (n = 145) Neonates who died (n = 63) Pvalue ORuadj (95% CI) ORadj (95% CI)
Maternal BMI, median (IQR) 27.5 (25.0-30.1) 25.6 (23.0-29.4) 0.06 0.91 (0.83-1.00) 1.05 (0.91-1.23)
Maternal Age, median years (IQR) 24.4 (20.9-27.9) 25.3 (22.5-28.6) 0.57 1.02 (0.96-1.08)  
Gestational age
Non-premature delivery (≥ 37 weeks) 76/145 (52.4) 12/63 (19.0)   Referent Referent
Preterm delivery (< 37 weeks) 69/145 (47.6) 51/63 (81.0) < 0.001 4.68 (2.31-9.51) 4.17 (1.19-14.56)
Comorbidities ** (%) 16/145 (11.0) 3 (4.8) 0.15 0.40 (0.11-1.44)  
Symptoms and Lab findings
CNS symptom (%) 10/145 (6.9) 13/63 (20.6) 0.005 3.51 (1.45-8.51) 0.85 (0.08-9.47)
AST (u/L), median (IQR) 40 (26-76) 73 (36-139) 0.01 1.00 (1.00-1.01) 1.00 (0.99-1.01)
PaO2/FiO2 on admission
PaO2/FiO2 ≥ 300 (%) 61/161 (37.9) 2/58 (3.4)   Referent Referent
PaO2/FiO2 201 to 300 (%) 22/161 (13.7) 3/58 (5.2) 0.13 4.16 (0.65-26.57) 3.59 (0.11-121.48)
PaO2/FiO2 ≤ 200 (%) 78/161 (48.4) 53/58 (91.4) < 0.001 20.72 (4.86-88.44) 12.33 (0.86-177.49)
APACHE II score, median (IQR) 8 (5-12) 10 (5-14) 0.17 1.04 (0.98-1.09) 0.99 (0.87-1.14)
  1. OR, Odds Ratio; CI, confidence Interval; ORuadj, unadjusted odds ratio; ORadj, Adjusted odds ratio; BMI, body mass index; IQR, interquartile range; APACHE II, acute physiology and chronic health evaluation II; ARDS, acute respiratory distress syndrome
  2. * Date are presented as no./total no., if otherwise stated. Percentages are based on women with complete information in the respective categories
  3. ** Comorbidities included respiratory diseases (asthma, COPD, active tuberculosis and other bronchial disease), cardiovascular diseases (heart disease, chronic congestive heart failure, valvular disease), diabetes mellitus, cancer or hematological diseases and Immune suppressed
  4. Values in the multivariate analysis included maternal BMI, gestational age, CNS symptom, AST, APACHE II score and PaO2/FiO2 on admission
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