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Table 3 Comparison between patients who succeeded with non-invasive ventilation and those who did not*

From: Clinical features and risk factors for severe and critical pregnant women with 2009 pandemic H1N1 influenza infection in China

Characteristic Non-invasive ventilation
  With successful outcomes‡ (n = 38) With failure outcomes (n = 45) Pvalue ORuadj (95% CI) ORadj (95% CI)
Age (Mean ± SD, years) 26.1 ± 4.3 25.5 ± 4.3 0.61 0.97 (0.88-1.08)  
BMI, median (IQR) 25.2 (24.4-28.8) 27.0 (24.5-30.4) 0.31 1.08 (0.93-1.25) 1.06 (0.72-1.56)
Gestational age, median (IQR) 32 (26-35) 32 (28-36) 0.96 0.99 (0.93-1.07) 0.97 (0.82-1.15)
Respiratory diseases (%) 2/37 (5.4) 1/44 (2.3) 0.48 0.42 (0.04-4.79)  
Pneumonia (%) 37/38 (97.4) 43/45 (95.6) 0.65 1.76 (0.15-20.23)  
Symptoms and Lab findings      
T ≥ 38°C(%) 33/37 (89.2) 39/42 (92.9) 0.86 1.57 (0.33-7.56)  
Dyspnoea (%) 24/38 (63.2) 31/44 (70.5) 0.43 0.68 (0.26-1.76)  
Hemoptysis (%) 6/38 (15.8) 9/43 (20.9) 0.62 1.34 (0.42-4.23)  
CNS symptom ※ (%) 1/38 (2.6) 9/44 (20.5) 0.04 9.51 (1.15-79.03) 1.48 (0.96-13.45)
WBC (×109/L), (Mean ± SD) 7.2 ± 3.6 7.6 ± 3.9 0.63 1.03 (0.91-1.16)  
Hb (g/L) (Mean ± SD) 105.9 ± 15.6 99.0 ± 15.7 0.06 0.97 (0.94-1.02)  
PLT (×109/L) (Mean ± SD) 155.5 ± 44.1 151.7 ± 56.7 0.75 1.00 (0.99-1.01)  
ALT (U/L) (Mean ± SD) 43.3 ± 60.9 48.9 ± 61.2 0.69 1.002 (0.99-1.01)  
CRP (mg/L) (Mean ± SD) 71.2 ± 52.9 90.8 ± 56.6 0.36 1.01 (0.99-1.02)  
PaO2/FiO2      
PaO2/FiO2 ≥ 300 (%) 7/24 (29.2) 3/33 (9.1)   Referent  
PaO2/FiO2 201 to 300 (%) 3/24 (12.5) 4/33 (12.1) 0.27 3.11 (0.41-23.93)  
PaO2/FiO2 ≤ 200 (%) 14/24 (58.3) 26/33 (78.8) 0.06 4.33 (0.97-23.83)  
APACHE II score, median (IQR) 7 (7-11) 10 (6-14) 0.01 1.14 (1.02-1.27) 1.20 (0.97-1.49)
Septic shock (%) 1/24 (4.2) 17/32 (53.1) 0.002 27.93 (3.34-33.47) 32.87 (1.91-566.52)
Acute liver damage **(%) 4/25 (16.0) 12/28 (42.9) 0.04 3.93 (1.07-14.52) 5.17 (0.47-56.37)
Pleural effusion (%) 11/35 (31.4) 12/40 (30.0) 0.89 1.07 (0.40-2.86)  
  1. ORuadj, unadjusted odds ratio; ORadj, Adjusted odds ratio; CI, confidence Interval; BMI, body mass index; IQR, interquartile range; APACHE II, acute physiology and chronic health evaluation II; ICU, intensive care unit
  2. * Date are presented as no./total no., if otherwise stated. Percentages are based on women with complete information in the respective categories
  3. ‡ included 38 patients survived after receiving NIV
  4. ¶ included 7 patients died of respiratory failure who received NIV, 38 patients who received NIV firstly, then changed to invasive ventilation
  5. ※ CNS system symptoms: refers to one or more of the following symptoms: insomnia, restlessness, hallucination, headache, dizziness and abnormal behaviour.
  6. ** Acute liver damage: AST or ALT > 70 U/L, or Tbil > 2 mg/dL.
  7. Variables included in multivariate model: BMI, Gestational age, CNS symptom, APACHE II score, septic shock, acute liver damage