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Table 2 Treatment, complications, outcomes among pregnant women with confirmed 2009 pH1N1 influenza and neonatal outcomes*

From: Clinical features and risk factors for severe and critical pregnant women with 2009 pandemic H1N1 influenza infection in China

Variables Value
Treatment
Antibiotics (%) 387/394 (98.2)
Corticosteroids (%) 242/394 (61.4)
Mechanical ventilation** (%) 186/394 (47.2)
Non-invasive ventilation, successful(%) 38/170 (22.4)
Non-invasive ventilation, failed (%) 45/170 (26.5)
Initially intubated (%) 87/170 (51.1)
Oseltamivir (%) 378/394 (95.9)
Interval from onset to oseltamivir ≤ 48 h (%) 52/371 (14.0)
Interval from onset to oseltamivir > 48 h (%) 319/371 (86.0)
Traditional Chinese Medicine (%) 244/392 (62.2)
Complications
ARDS (%) 151/283 (53.4)
Septic shock (%) 51/254 (20.1)
Acute renal failure (%) 11/237 (4.6)
Acute liver damage‡ (%) 73/260 (28.1)
DIC (%) 8/234 (3.4)
Clinical course and Maternal Outcomes  
ICU admission (%) 246/386 (63.7)
Length of ICU stay, median (IQR) 8 (5-14)
Time from onset to fever clearance, median (IQR) 7 (5-10)
Hospital stay for survivors, median (IQR) 11 (7-17)
In-hospital mortality (%) 77/394 (19.5)
Time from onset to death, median (IQR) 11 (7-17)
Delivery methods
Vaginal delivery (%) 31/208 (14.9)
Vacuum-assisted vaginal delivery (%) 2/208 (1.0)
Forceps-assisted vaginal delivery (%) 3/208 (1.4)
Cesarean delivery (%) 172/208 (82.7)
Neonatal outcomes
Survival 146/208 (70.2)
Stillbirth 36/208 (17.3)
Neonatal death 12/208 (4.8)
Spontaneous abortion 1/208 (0.5)
Therapeutic abortion 13/208 (6.3)
  1. ARDS, acute respiratory distress syndrome; DIC, disseminated intravascular coagulation; ICU, intensive care unit; IQR, interquartile range.
  2. * Date are presented as no./total no. if otherwise stated. Percentages are based on women with complete information in the respective categories.
  3. ** Sixteen patients missed the strategies of mechanical ventilation.
  4. ¶¶Acute renal failure: Serum Creatinine increased by 2-fold or GFR decreased > 50%, or urine   0.5 ml/kg/h for at least 12 h.
  5. ‡ Acute liver damage: AST or ALT > 70 U/L, or Tbil > 2 mg/dL