Table 2 Treatment, complications, outcomes among pregnant women with confirmed 2009 pH1N1 influenza and neonatal outcomes*
Variables | Value |
|---|---|
Treatment | |
Antibiotics (%) | 387/394 (98.2) |
Corticosteroids (%) | 242/394 (61.4) |
Mechanical ventilation** (%) | 186/394 (47.2) |
Non-invasive ventilation, successful(%) | 38/170 (22.4) |
Non-invasive ventilation, failed (%) | 45/170 (26.5) |
Initially intubated (%) | 87/170 (51.1) |
Oseltamivir (%) | 378/394 (95.9) |
Interval from onset to oseltamivir ≤ 48 h (%) | 52/371 (14.0) |
Interval from onset to oseltamivir > 48 h (%) | 319/371 (86.0) |
Traditional Chinese Medicine (%) | 244/392 (62.2) |
Complications | |
ARDS (%) | 151/283 (53.4) |
Septic shock (%) | 51/254 (20.1) |
Acute renal failure (%) | 11/237 (4.6) |
Acute liver damage‡ (%) | 73/260 (28.1) |
DIC (%) | 8/234 (3.4) |
Clinical course and Maternal Outcomes | Â |
ICU admission (%) | 246/386 (63.7) |
Length of ICU stay, median (IQR) | 8 (5-14) |
Time from onset to fever clearance, median (IQR) | 7 (5-10) |
Hospital stay for survivors, median (IQR) | 11 (7-17) |
In-hospital mortality (%) | 77/394 (19.5) |
Time from onset to death, median (IQR) | 11 (7-17) |
Delivery methods | |
Vaginal delivery (%) | 31/208 (14.9) |
Vacuum-assisted vaginal delivery (%) | 2/208 (1.0) |
Forceps-assisted vaginal delivery (%) | 3/208 (1.4) |
Cesarean delivery (%) | 172/208 (82.7) |
Neonatal outcomes | |
Survival | 146/208 (70.2) |
Stillbirth | 36/208 (17.3) |
Neonatal death | 12/208 (4.8) |
Spontaneous abortion | 1/208 (0.5) |
Therapeutic abortion | 13/208 (6.3) |