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Table 5 Characteristics of culture positive patients with HAP and VAP with regard to the adequacy of empirical antibiotic treatment

From: Inadequate treatment of ventilator-associated and hospital-acquired pneumonia: Risk factors and impact on outcomes

Characteristics

 

HAP (n = 94)

  

VAP (n = 117)

 
 

Adequate treatment n = 43 (%)

Inadequate treatment n = 51 (%)

p

Adequate treatment n = 37 (%)

Inadequate treatment n = 80 (%)

p

Age (years)

60.67 ± 16.04

65.14 ± 13.75

0.167

63.59 ± 16.65

63.85 ± 17.07

0.907

Sex (male)

32(74.4)

37 (72.5)

1.000

24 (64.9)

45 (56.3)

0.497

Surgical unit

9 (20.9)

8 (15.7)

0.697

21 (56.8)

25 (31.3)

0.015

Underlying diseases

      

 Diabetes mellitus

5 (11.6)

8 (15.7)

0.789

5 (13.5)

11 (13.8)

1.000

 COPD

13 ( 30.2)

10 (19.6)

0.341

11 (29.7)

17 (21.3)

0.443

 Chronic renal failure

5 (11.6)

4 (7.8)

0.727

0 (0)

3 (3.8)

0.551

 Congestive heart failure

4 (9.3)

9 (17.6)

0.386

6 (16.2)

13 (16.3)

1.000

 Cerebrovascular disease

1 (2.3)

9 (17.6)

0.019

3 (8.1)

15 (18.8)

0.227

 Malignancy

6 (14.0)

9 (17.6)

0.838

6 (16.2)

11 (13.8)

0.944

Central venous catheterization

16 (37.2)

22 (43.1)

0.710

30 (81.1)

58 (72.5)

0.442

Urinary catheterization

33 (76.7)

37 (72.5)

0.820

37 (100)

78 (97.5)

1.000

Late-onset pneumonia

34 (79.1)

46 (90.2)

0.223

34 (91.9)

72 (90)

1.000

Acquisition of other site infection

12 (27.9)

11 (21.6)

0.637

11 (29.7)

42 (52.5)

0.036

Previous antibiotic usage

20 (46.5)

23 (45.1)

1.000

11 (29.7)

36 (45.0)

0.173

MDR bacteria

29 (67.4)

38 (74.5)

0.599

32 (86.5)

60 (75)

0.243

Polymicrobial etiology

1 (2.3)

8 (15.7)

0.036

2 (5.4)

6 (7.5)

1.000

Length of stay before HAP

7.6 ± 4.3

9.18 ± 5.8

0.194

13.89 ± 11.56

14.88 ± 10.34

0.313

APACHE II score

12.7 ± 5.83

14.92 ± 5.83

0.031

16.08 ± 6.94

16.69 ± 6.72

0.654

Exitus

16 (37.2)

24 (47.1)

0.452

27 (73)

53 (66.3)

0.608