Empiric antibiotic | HAP (n = 218) | VAP (n = 130) | ||||
---|---|---|---|---|---|---|
Adequate (n = 128) | Inadequate (n = 90) | p | Adequate (n = 44) | Inadequate (n = 86) | p | |
Carbapenems | 31 (24.2) | 16 (17.8) | 0.004 | 20 (45.5) | 18 (20.9) | <0.001 |
Third generation cefalosporine | 31 (24.2) | 27 (30.0) | 4 (9.1) | 20 (23.3) | ||
β-lactam + β- lactamase inhibitor | 35 (27.3) | 21 (23.3) | 14 (31.8) | 26 (30.2) | ||
Quinolone | 21 (16.4) | 16 (17.8) | 0 | 10 (11.6) | ||
β-lactam in combination with quinolone | 1 (0.8) | 9 (10.0) | 0 | 9 (10.5) | ||
Aminoglycoside in combination with carbapenem or β-lactam | 9 (7.0) | 1 (1.1) | 6 (13.6) | 3 (3.5) |