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Table 3 Characteristics of patients with posaconazole level monitoring

From: Analysis of posaconazole as oral antifungal prophylaxis in pediatric patients under 12 years of age following allogeneic stem cell transplantation

Characteristic Posaconazole administration
  2 x per day (n = 6) 3 x per day (n = 8)
  No. of patients (%)
Gender   
 Male 2 (33.3) 5 (62.5)
 Female 4 (66.6) 3 (37.5)
Age group   
 < 6 years 3 (5.0) 6 (75.0)
 6-11 years 3 (5.0) 2 (25.0)
Donor   
 MUD 2 (33.3) 3 (37.5)
 MMFD 2 (33.3) 5 (62.2)
 MFD 2 (33.3) 0 (0)
Primary diagnosis   
 ALL 1 (16.7) 2 (25.0)
 Biphenotypic leukemia 0 (0) 1 (12.5)
 Solid tumors 1 (16.7) 0 (0)
 Aplastic anemia 2 (33.3) 1 (12.5)
 Neurometabolic diseases 1 (16.7) 1 (12.5)
 Immunodeficiency 1 (16.7) 3 (37.5)
Graft-versus-Host disease   
 Grade I 2 (33.3) 2 (25.0)
 Grade II 0 (0) 2 (25.0)
 Grade III 0 (0) 0 (0)
 Grade IV 0 (0) 0 (0)
 Chronic limited 0 (0) 0 (0)
 Chronic extensive 0 (0) 0 (0)
  1. Abbreviation: ALL, indicates acute lymphoblastic leukemia; MFD, matched family donor; MMFD, mismatched family donor; MUD, matched unrelated donor.