Patient 1
|
−2
|
First visit to ARV clinic
|
23
|
5
|
13
|
152
|
73
|
7.4
|
6.5
|
394
|
n/a
| |
0
| |
26
|
11
|
20
|
131
|
89
|
8.0
|
5.5
|
314
|
n/a
| |
+2
|
Presents with jaundice 2 weeks post HAART
|
20
|
88*
|
127
|
833
|
429
|
7.0
|
3.1
|
803
|
2.9
|
1.3
|
+4
|
Starts 14 days prednisolone
|
17
|
62
|
99
|
1310
|
673
|
7.0
|
2.9
|
736
|
n/a
|
1.0
|
+8
|
Clinically improved
|
24
|
22
|
49
|
667
|
330
|
7.9
|
3.9
|
448
|
n/a
|
1.0
|
Patient 5
|
−2
|
First visit to ARV clinic
|
22
|
18
|
34
|
119
|
35
|
11.3
|
5.4
|
364
|
n/a
|
n/a
|
0
|
After 2 weeks TB treatment starts HAART
|
24
|
21
|
45
|
133
|
57
|
9.3
|
4.4
|
682
|
n/a
|
n/a
|
+2
|
Has been found to have jaundice 10 days post HAART; TB treatment stopped
|
21
|
56*
|
60
|
115
|
99
|
n/a
|
n/a
|
n/a
|
2.7
|
1.3
|
+3
|
With resolving jaundice and clinical deterioration TB treatment restarted
|
26
|
26
|
48
|
138
|
93
|
9.5
|
2.6
|
460
|
2.6
|
1.2
|
+4
|
Return of jaundice and liver biopsy suggests DILI – TB treatment stopped
|
21
|
97
|
67
|
187
|
148
|
9.2
|
2.7
|
424
|
1.6
|
1.4
|