Prediction of cervical intraepithelial neoplasia grade 2+ (CIN2+) using HPV DNA testing after a diagnosis of atypical squamous cell of undetermined significance (ASC-US) in Catalonia, Spain

Table 2 Diagnosis at last follow up^&among 493 women with ASC-US from 5 sentinel screening centres in Catalonia (Spain) by hrHPV status

	TOTAL CASES	POSITIVE hrHPV		NEGATIVE hrHPV
Diagnosis at last follow up^{& 1}	N	N	%	N	%
Normal	341	108	31.7	233	68.3
No histology confirmation:
ASC-US	13	6	46.2	7	53.8
hrHPV+	46	37	80.4	9	19.6
CIN-NOS	1	1	100.0	0	0.0
LSIL	33	30	90.9	3	9.1
HSIL*	1	1	100.0	0	0.0
With histology confirmation:
CIN1	22	20	90.9	2	9.1
CIN-2	18	17	94.4	1	5.6
CIN-3	16	16	100.0	0	0.0
Cancer	2	2	100.0	0	0.0
Total	493	238	48.3	255	51.7

^&Maximum follow up 3.5 years
¹ ASC-US: Atypical squamous cell of undetermined significance, HPV+: positive for Human Papillomavirus test, CIN-NOS: CIN not otherwise specified, CIN1: high grade cervical intraepithelial lesions grade 1, LSIL: low grade squamous intraepithelial lesion, CIN1: high grade cervical intraepithelial lesions grade 1, CIN2: high grade cervical intraepithelial lesions grade 2, CIN3: high grade cervical intraepithelial lesions grade 3, HSIL: High grade squamous intraepithelial lesion
* The HSIL case could not be specified as CIN2 or CIN3

ISSN: 1471-2334