|
Variable
|
Unadjusted
|
Adjusted
|
|---|
| |
OR (95% CI)
| |
P
|
OR (95% CI)
|
P
|
|---|
|
Demographic characteristics
| | | |
|
Age
| | | | |
|
0-9
|
4.2
|
(1.7, 10.3)
|
0.002
|
5.1
|
(1.7, 15.3)
|
0.004
|
|
10-19
|
1.3
|
(0.4, 4.3)
|
0.682
|
2.4
|
(0.6, 10.0)
|
0.213
|
|
20-29 (reference)
|
1.0
| | |
1.0
| | |
|
30-39
|
2.4
|
(1.0, 6.0)
|
0.059
|
2.7
|
(0.9, 8.4)
|
0.078
|
|
40-49
|
4.8
|
(2.1, 11.2)
|
<0.001
|
7.1
|
(2.5, 19.9)
|
<0.001
|
|
50-59
|
7.1
|
(3.1, 16.4)
|
<0.001
|
8.5
|
(3.1, 23.6)
|
<0.001
|
|
60-69
|
10.6
|
(4.7, 24.1)
|
<0.001
|
14.8
|
(5.4, 40.6)
|
<0.001
|
|
70-79
|
18.8
|
(8.3, 42.6)
|
<0.001
|
23.8
|
(8.7, 65.1)
|
<0.001
|
|
80-89
|
29.3
|
(12.9, 66.3)
|
<0.001
|
38.1
|
(13.9, 104)
|
<0.001
|
|
90+
|
46.2
|
(19.8, 108)
|
<0.001
|
54.4
|
(19.1, 154)
|
<0.001
|
|
Sex
| | | | | | |
|
Female
|
1.0
| | | | | |
|
Male
|
1.0
|
(0.9, 1.2)
|
0.838
| | | |
|
Ethnicity
| | | | | | |
|
Indigenous
|
1.0
| | | | | |
|
Asian
|
2.7
|
(1.7, 4.2)
|
<0.001
| | | |
|
Caucasian
|
3.1
|
(2.2, 4.3)
|
<0.001
| | | |
|
Polynesian
|
1.7
|
(0.9, 3.4)
|
0.131
| | | |
|
Other
|
1.7
|
(1.0, 3.0)
|
0.052
| | | |
|
IRSAD quintile
| | | | | | |
|
1
|
1.0
| | | | | |
|
2
|
1.3
|
(1.0, 1.7)
|
0.033
| | | |
|
3
|
1.3
|
(1.0, 1.6)
|
0.050
| | | |
|
4
|
1.2
|
(1.0, 1.5)
|
0.091
| | | |
|
5
|
1.3
|
(1.0, 1.6)
|
0.026
| | | |
|
Risk factors and Acquisition
| | | | | | |
|
Dialysis
| | | | | | |
|
No
|
1.0
| | | | | |
|
Yes
|
0.7
|
(0.5, 0.8)
|
<0.001
| | | |
|
IDU
| | | | | | |
|
No
|
1.0
| | | | | |
|
Yes
|
0.3
|
(0.2, 0.4)
|
<0.001
| | | |
|
Acquisition
| | | | | | |
|
Community onset
|
1.0
| | | | | |
|
Community onset HCA
|
2.1
|
(1.7, 2.5)
|
<0.001
|
1.4
|
(1.1,1.7)
|
0.011
|
|
Nosocomial
|
2.4
|
(2.0, 2.9)
|
<0.001
|
1.5
|
(1.2,1.9)
|
0.001
|
|
Microbiology and antibiotics
| | | | | | |
|
Susceptibility
| | | | | | |
|
MSSA
|
1.0
| | | | | |
|
cMRSA
|
1.3
|
(1.0, 1.6)
|
0.025
| | | |
|
eMRSA
|
2.0
|
(1.7, 2.3)
|
<0.001
| | | |
|
Antibiotic treatment
| | | | | | |
|
β-lactam
|
1.0
| | | | | |
|
Glycopeptide
|
2.0
|
(1.7, 2.3)
|
<0.001
|
1.5
|
(1.3, 1.8)
|
<0.001
|
|
Other
|
2.1
|
(1.6, 2.8)
|
<0.001
|
1.6
|
(1.2, 2.2)
|
0.002
|
|
Clinical infection
| | | | | | |
|
Primary focus
| | | | | | |
|
SSTI
|
1.0
| | |
1.0
| | |
|
Device with 2° infection
|
1.8
|
(1.2, 2.7)
|
0.003
|
1.9
|
(1.3, 2.9)
|
0.003
|
|
Device with no 2° infection
|
0.8
|
(0.7, 1.0)
|
0.118
|
0.9
|
(0.7, 1.2)
|
0.600
|
|
IE Left sided
|
1.5
|
(1.0, 2.1)
|
0.025
|
2.2
|
(1.5, 3.2)
|
<0.001
|
|
IE Right sided
|
0.6
|
(0.3, 1.1)
|
0.092
|
1.4
|
(0.7, 3.0)
|
0.308
|
|
No focus
|
1.9
|
(1.6, 2.4)
|
<0.001
|
1.4
|
(1.1, 1.9)
|
0.011
|
|
Bone/joint
|
0.6
|
(0.4, 0.8)
|
<0.001
|
0.8
|
(0.6, 1.1)
|
0.228
|
|
Respiratory
|
3.7
|
(2.9, 4.8)
|
<0.001
|
3.6
|
(2.7, 4.8)
|
<0.001
|
|
Sepsis
|
4.4
|
(3.5, 5.5)
|
<0.001
|
4.0
|
(3.1, 5.3)
|
<0.001
|
|
ICU
| | | | | | |
|
No
|
1.0
| | |
1.0
| | |
|
Yes
|
1.8
|
(1.5, 2.1)
|
<0.001
|
2.2
|
(1.8, 2.7)
|
<0.001
|
-
Note. Adjusted odds ratios and P values are only displayed if that variable was significant in the final multivariate model. OR, odds ratio; CI, confidence interval; IRSAD, Index of Relative Socio-economic Advantage or Disadvantage; HCA, healthcare-associated; MSSA, methicillin-susceptible S. aureus; cMRSA, community-associated methicillin-resistant S. aureus; eMRSA, epidemic MRSA; SSTI, skin and soft tissue infection; IE, infective endocarditis; ICU, intensive care unit.
