Procalcitonin and procalcitonin kinetics for diagnosis and prognosis of intravascular catheter-related bloodstream infections in selected critically ill patients: a prospective observational study

Table 1 Patient’s demographics and clinical characteristics on admission and final outcome

	Not proven CRBSI	Proven CRBSI	P
	n = 20	n = 26
Age [years; mean (SD)]	44.45 (19.75)	51.73 (19.95)	0.224^a
Male gender [no (%)]	10 (50.0)	18 (69.2)	0.185^b
Origin [no (%)]
Medical	9 (45.0)	12 (46.2)	0.938^b
Surgical	11 (55.0)	14 (53.8)
Reason of admission [no (%)]
Neurological	13 (65.0)	12 (46.2)	0.203^b
Respiratory	1 (5.0)	2 (7.7)	0.714^b
Surgical	1 (5.0)	4 (15.4)	0.262^b
Trauma	4 (20.0)	6 (23.0)	0.802^b
Other	1 (5.0)	2 (7.7)	0.714^b
APACHE II score [mean (SD)]	22.45 (4.32)	20.65 (4.69)	0.190^a
SOFA score [mean (SD)]	7.15 (1.57)	6.81 (2.53)	0.598^a
Presence of SIRS [no (%)]	6 (30.0)	9 (34.6)	0.741^b
Co-morbidities
Malignancy [no (%)]	1 (5.0)	2 (7.7)	0.714^b
Diabetes mellitus [no (%)]	2 (10.0)	3 (11.5)	0.868 ^b
Steroids [no (%)]	2 (10.0)	3 (11.5)	0.868^b
Heart failure [no (%)]	1 (5.0)	2 (7.7)	0.714^b
WBC count [10 ³/μl; mean (SD)]	14.47 (4.2)	12.80 (4.1)	0.185^a
CRP [mg/dl; median (IQR)]	0.86 (0.50-2.65)	2.68 (0.62-10.88)	0.069^c
PCT [ng/mL; median (IQR)]	0.10 (0.10-0.20)	0.10 (0.10-0.43)	0.168^c
ICU length of stay [days; mean (SD)]	19.85 (6.99)	29.15 (11.34)	0.001^a
ICU mortality [no (%)]	1 (5.0)	5 (19.2)	0.155^b

ISSN: 1471-2334