Table 3 Mortality among patients with E. coli or Klebsiella spp. bacteremia treated empirically with different antimicrobials depending on the adequacy
Adequate | Inadequate | p | RR (95% CI) | |
|---|---|---|---|---|
Beta-lactam/Beta-lactam inhibitor combinations (n = 117) | 11 (13.1) | 13 (39.4) | 0.002 | 0.58 (0.37-0.91) |
Amoxicillin/clavulanate (n = 67) | 3 (7.5) | 10 (37) | 0.004 | 0.34 (0.12-0.92) |
Piperacillin/tazobactam (n = 50) | 8 (18.2) | 3 (50) | 0.11 | 0.79 (0.54-1.14) |
Quinolones (n = 62) | 0) | 10 (20.4) | - | - |
Carbapenem (n = 70) | 18 (25.7) | - | - | - |
Cefotaxime or ceftriaxone (n = 50) | - | 7 (14) | - | - |
Aminoglycoside monotherapy* (n = 22) | 3 (23.1) | 2 (22.2) | 0.68 | 1.02 (0.45-2.31) |
None antimicrobial (n = 25) | - | 7 (28) | - | - |
Overall (n = 387) | 34 (17.2) | 47 (24.9) | 0.04 | 0.78 (0.59-1.03) |