| CA-KpBSI | HCA-KpBSI | p |
---|---|---|---|
(n = 240) | (n = 313) | ||
Age (years) (mean ±SD) | 63.0 (±13.6) | 60.3 (±12.9) | 0.015 |
Male sex | 142 (59.2) | 206 (65.8) | 0.124 |
Underlying disease | |||
  Diabetes mellitus | 74 (30.8) | 71 (22.7) | 0.031 |
  Chronic liver disease | 39 (16.3) | 84 (26.8) | 0.003 |
  Biliary tract disease | 42 (17.5) | 43 (13.7) | 0.224 |
  Chronic kidney disease | 13 (5.4) | 19 (6.1) | 0.774 |
  Respiratory disease | 18 (7.5) | 21 (6.7) | 0.719 |
  Solid tumor | 58 (24.2) | 180 (57.5) | <0.001 |
  Hematologic malignancy | 4 (1.7) | 23 (7.3) | 0.002 |
  Solid organ transplantation | 5 (2.1) | 9 (2.9) | 0.557 |
Charlson’s WIC (≥3) | 47 (19.6) | 141 (45.0) | <0.001 |
Primary infection site | |||
  Urinary tract | 31 (12.9) | 34 (10.9) | 0.457 |
  Peritoneum | 11 (4.6) | 46 (14.7) | <0.001 |
  Pancreatobiliary tract | 82 (34.2) | 102 (32.6) | 0.696 |
  Liver | 67 (27.9) | 41 (13.1) | <0.001 |
  Lung | 16 (6.7) | 28 (8.9) | 0.326 |
  Skin and soft tissue | 4 (1.7) | 8 (2.6) | 0.477 |
  Bone | 4 (1.7) | 2 (0.6) | 0.411 |
  Central nervous system | 1 (0.4) | 0 (0) | 0.434 |
  Othersa | 1 (0.4) | 3 (1.0) | 0.637 |
  Unknown | 21 (8.8) | 52 (16.6) | 0.007 |
Metastatic infection | 11 (4.6) | 9 (2.9) | 0.286 |
Endophthalmitis | 5 (2.1) | 3 (1.0) | 0.303 |
Pitt bacteremia score (≥4) | 36 (15.0) | 56 (17.9) | 0.366 |
Shock at presentation | 55 (22.9) | 101 (32.3) | 0.015 |
Neutropenia at presentation | 3 (1.3) | 42 (13.4) | <0.001 |
Polymicrobial infection | 34 (14.2) | 47 (15.0) | 0.780 |
Initial antimicrobial regimen | |||
  Piperacillin-tazobactam | 9 (3.8) | 30 (9.6) | 0.008 |
  Quinolone | 23 (9.6) | 18 (5.8) | 0.088 |
  1st generation cephalosporin | 2 (0.8) | 0 (0) | 0.188 |
  3rd generation cephalosporin | 173 (72.1) | 186 (59.4) | 0.002 |
  Carbapenem | 30 (12.5) | 48 (15.3) | 0.342 |
Inappropriate empirical antimicrobial therapy | 14 (5.8) | 26 (8.3) | 0.266 |
Inappropriate definitive antimicrobial therapyb | 7/223 (3.1) | 7/278 (2.5) | 0.675 |
30-day mortality | 27 (11.3) | 70 (22.4) | 0.001 |