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Table 2 Diagnostic performance of conventional nested Aspergillus PCR a

From: Aspergillus-PCR in bronchoalveolar lavage for detection of invasive pulmonary aspergillosis in immunocompromised patients

  Sensitivity Specificity PPV NPV
As compared to EORTC/NIAID     
Proven 0% 71% 0% 98%
Proven & Probable 36% 72% 7% 95%
Proven & Probable & Possible 26% 70% 26% 71%
As compared to clinical judgment     
Receiving antifungal therapy 30% 73% 60% 43%
Suspicion of IFD on radiologic studies 28% 71% 27% 72%
  1. IFD = invasive fungal disease.