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Table 1 Number of articles reporting subject and laboratory characteristics stratified by exposure route

From: Variation in dengue virus plaque reduction neutralization testing: systematic review and pooled analysis

  Vaccination Natural Exposure Total
Geographic location of study population
Asia 2 15 17
North America 5 11 15*
South America 0 1 1
Africa 0 0 0
Australia 1 0 1
Europe 0 2 2
Not reported 1 1 1*
Neutralization percentage
50 % 5 18 23
70 % 0 3 3
80 % 2 2 3*
90 % 0 1 1
Not reported 1 2 3
Cell line
BHK 0 9 9
LLC-MK2 5 11 16
Vero 3 4 6*
Not reported 0 2 2
Virus concentration (plaque-forming units [pfu] or focus-forming units [ffu] per microliter [uL] or milliliter [mL])
10-20 pfu / 10 uL 0 1 1
10-20 pfu / 50 uL 0 2 2
15-25 pfu / 25 uL 0 2 2
20-30 pfu / 12.5 uL 0 2 2
40-80 pfu / 100 uL 0 1 1
50 pfu / 150 uL 3 4 7
107 pfu / mL 2 0 2
25-50 pfu 0 1 1
50 pfu 0 1 1
320 pfu 0 1 1
100 ffu / 90 uL 0 1 1
800 ffu 1 1 1*
Not reported 2 8 10
  1. * indicates articles do not sum in row as Vasilakis et al. [18] reported titers from vaccination and natural exposure.