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Table 4 Proteus mirabilis . and Klebsiella spp non-susceptibility rates a for cases with available clinical data

From: Cefditoren: Comparative efficacy with other antimicrobials and risk factors for resistance in clinical isolates causing UTIs in outpatients

Antimicrobial agent Proteus mirabilis Klebsiellaspp.
AUCb(n = 31) Total cases with available clinical information (n = 75) AUCb(n = 22) Total cases with available clinical information (n = 45)
Amoxicillin 35.5 33.3 N/A c N/A c
Amoxicillin/clavulanic acid 6.5 5.3 0 2.2
Cefalothin 12.9 12.0 4.5 4.4
Cefuroxime sodium 0 2.7 0 0
Cefuroxime axetil 3.2 5.3 4.5 2.2
Co-trimoxazole 16.1 16 9.1 11.1
Nalidixic acid 9.7 6.7 0* 8.9
Ciprofloxacin 6.5 2.7 0 4.4
Mecillinam 25.8 21.3 0 0
Nitrofurantoin N/A c N/A c 40.9 33.3
Fosfomycin 0 0 0 2.2
Cefotaxime 3.2 3.2 0 0
Ceftazidime 6.5 5.3 0 0
Gentamicin 0 2.7 0  
Netilimicin 0 0 0 2.2
Amikacin 0 0 4.5 4.4
Piperacillin-tazobactam 0 0 0 0
Ticarcillin-clavulanate 0 0 0 0
Imipenem 0 0 0 0
Cefditoren 3.2 2.7 0 2.2
  1. a CLSI 2011 breakpoints of susceptibility were applied; b Acute Uncomplicated Cystitis, c not applicable, , *P ≤ 0.05.