Table 4 Summary of cagA and vacA s, m, and i genotypes in relation to peptic ulcer disease and gastric cancer risk
| Â | Â | Â | Â | cagAgenotype | vacAgenotype | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Disease | Paper (n) | Patient (n) | cagA(n/%) | Western EPIYA-ABC | East-Asian EPIYA-ABD | s1 (n/%) | s1a (n/%) | s1b (n/%) | s1c (n/%) | s2 (n/%) | m1 (n/%) | m2 (n/%) | s1m1 (n/%) | s1m2 (n/%) | s2m1 (n/%) | s2m2 (n/%) | i1 (n/%) | i2 (n/%) |
NUD | 8 | 604 | 555 (92) | 127 (44) | 160 (56) | 414 (99) | 62 (63) | 4 (4) | 33 (33) | 4 (1) | 224 (55) | 185 (45) | 224 (55) | 180 (44) | 0 (0) | 4 (1) | 186 (94) | 11 (6) |
PU | 8 | 279 | 264 (95) | 11* (21) | 42 (79) | 236 (100) | 38 (64) | 1 (2) | 20 (33) | 1 (0) | 135 (59) | 92 (41) | 134 (59) | 92 (41) | 0 (0) | 1 (0) | 40 (100) | 0 (0) |
GC | 5 | 74 | 73 (99) | 9* (17) | 45 (83) | 42 (100) | 2 (67) | 0 (0) | 1 (33) | 0 (0) | 22 (54) | 19 (46) | 22 (54) | 19 (46) | 0 (0) | 0 (0) | 22 (100) | 0 (0) |
Total | Â | 957 | 892 (93) | 147 (37) | 247 (63) | 692 (99) | 102 (63) | 5 (3) | 54 (34) | 5 (1) | 380 (56) | 296 (44) | 380 (56) | 291 (43) | 0 (0) | 5 (1) | 248 (96) | 11 (4) |