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Table 2 Summary of cagA status , EPIYA motif genotype, and vacA s-, m- and i-region genotypes in different Southeast Asian countries

From: Role of Helicobacter pylori cagA EPIYA motif and vacAgenotypes for the development of gastrointestinal diseases in Southeast Asian countries: a meta-analysis

    

cagAgenotype

vacAgenotype

 

Paper (n)

Patient (n)

cagA(n/%)

Western EPIYA-ABC

East-Asian EPIYA-ABD

s1 (n/%)

s1a (n/%)

s1b (n/%)

s1c (n/%)

s2 (n/%)

m1 (n/%)

m2 (n/%)

s1m1 (n/%)

s1m2 (n/%)

s2m1 (n/%)

s2m2 (n/%)

i1 (n/%)

i2 (n/%)

Vietnam

4

250

239 (96)

5 (3)

139 (97)

228 (100)

NA

NA

NA

1 (0)

106 (48)

117 (52)

106 (48)

117 (52)

0 (0)

0 (0)

94 (94)

6 (6)

Thailand

4

345

327 (95)

50 (51)

48* (49)

342 (100)

107 (62)

0 (0)

66 (38)

0 (0)

215* (65)

116 (35)

215* (65)

116 (35)

0 (0)

0 (0)

NA

NA

Malaysia

5

578

324 (90)

160 (43)

215* (57)

337 (94)

33 (51)

4 (6)

28 (43)

22 (6)

221* (62)

138 (38)

221* (62)

124 (35)

0 (0)

14 (4)

154 (97)

5 (3)

Singapore

1

108

95 (88)

NA

NA

103 (99)

NA

NA

NA

1 (1)

39 (38)

65 (63)

39 (38)

64 (62)

0 (0)

1 (1)

NA

NA

Total

13

1281

985 (93)

215 (35)

402 (65)

1010 (98)

140 (59)

4 (2)

94 (39)

24 (2)

581 (58)

436 (42)

581 (58)

421 (42)

0 (0)

15 (1)

248 (96)

11 (4)

  1. ‘NA’ (not available) indicates a lack of no data associating cagA status, EPIYA motif genotype, and vacA s-, m-, and i-region genotypes. As a report from Yamaoka Y, et al. included two populations: Vietnamese and Thai [7], the number of studies was reduced by one.
  2. *: p < 0.05 (significant differences among different countries, when compared with Vietnam.) by use of chi-square test.