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Table 1 Reported cagA genotypes and vacA s, m, and i regions genotypes and cagA status in studies used in the present meta-analysis

From: Role of Helicobacter pylori cagA EPIYA motif and vacAgenotypes for the development of gastrointestinal diseases in Southeast Asian countries: a meta-analysis

     

cagAgenotype

vacAgenotype

Area/country

Authors

Year

Patients (n)*

cagA

ABC

ABCC/ABCCC

ABD

2a

1a

s1 (n/%)

s2 (n/%)

m1 (n/%)

m2 (n/%)

i1 (n/%)

i2 (n/%)

Vietnam

Yamaoka Y [7]

2002

25 S

24 (96)

NA

NA

NA

0 (0)

24 (100)

25 (100)

0 (0)

14 (56)

11 (44)

NA

NA

Vietnam

Uchida T [31]

2009

103 S

98 (95)

4 (4)

0 (0)

94 (96)

NA

NA

103

(100)

1 (1)

44 (45)

54 (55)

NA

NA

Vietnam

Truong BX [32]]

2009

22 S

22 (100)

1 (5)

0 (0)

21 (95)

NA

NA

NA

NA

NA

NA

NA

NA

Vietnam

Nguyen TL [33]

2010

100

95 (95)

NA

NA

NA

NA

NA

100 (100)

0 (0)

48 (48)

52 (52)

94 (94)

6 (6)

Thailand

Yamaoka Y [7]

2002

8 S

8 (100)

NA

NA

NA

4 (50)

4 (50)

8 (100)

0 (0)

6 (75)

2 (25)

NA

NA

Thailand

Vilaichone RK [34]

2004

98 S

98 (100)

NA

NA

NA

50 (51)

48 (49)

98 (100)

0 (0)

71 (72)

27 (28)

NA

NA

Thailand

Linpisarn S [35]

2007

135

119 (88)

NA

NA

NA

NA

NA

132 (100)

0 (0)

73 (63)

42 (37)

NA

NA

Thailand

Chomvarin C [36]

2008

112 S

110 (98)

NA

NA

NA

NA

NA

112 (100)

0 (0)

65 (58)

47 (42)

NA

NA

Malaysia

Tan HJ [37]

2005

127 S

107 (84)

NA

NA

NA

NA

NA

117 (92)

10 (8)

81 (64)

46 (36)

NA

NA

Malaysia

Tan HJ [38]

2006

73 S

58 (79)

NA

NA

NA

NA

NA

65 (89)

8 (11)

46 (63)

27 (37)

NA

NA

Malaysia

Mohamed R [39]

2009

93

NA

23 (22)

13 (12)

70 (66)

NA

NA

NA

NA

NA

NA

NA

NA

Malaysia

Schmidt HMA [40]

2009

126 S

NA

34 (28)

19 (16)

68 (56)

NA

NA

NA

NA

NA

NA

NA

NA

Malaysia

Schmidt HMA [41]

2010

159 S

159 (100)

71 (45)

0 (0)

88 (55)

NA

NA

155 (97)

4 (3)

94 (59)

65 (41)

154 (97)

5 (3)

Singapore

Zheng PY [42]

2000

108 S

95 (88)

NA

NA

NA

NA

NA

103 (99)

1 (1)

39 (38)

65(62)

NA

NA

  1. ‘NA’ (not available) indicates a lack of data associating cagA status, EPIYA motif genotype, and vacA s-, m-, and i-region genotypes.
  2. The uppercase ‘s’ indicates the use of single colonies and the remaining studies refer to the use of gastric biopsy samples, paraffin-embedded biopsy samples, and pools of cultured colonies.