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Table 3 Logistic regression analysis of factors associated with risk of complicated malaria

From: Complicated malaria and other severe febrile illness in a pediatric ward in Libreville, Gabon

Variables Malaria ORa[95%CI]b p aORc[95%CI] p
  Prevalence     
Age      
  - ≥ 5 years (n = 86) 32 (37.2%) 2.6[1.5-4.3] <0.01 2.5[1.3-4.7] <0.01
  - < 5 years (n = 332) 63 (19.0%) 1    
Bed net      
  - users (n = 276) 47 (17.0%) 0.4[0.2-0.6] <0.01 0.4[0.2-0.7] <0.01
  - non users (n = 129 44 (34.1%) 1    
Drug intake      
  -Yesd (n = 95) 41 (43.2%) 0.5[0.3-0.8] <0.01 1.3[0.8-2.3] 0.3
  -Nod (n = 323) 93 (28.8%) 1    
Pallor      
  -Yes (n = 95) 66 (69.5%) 2.8[1.7-4.0] <0.01 2.9[1.7-5.2] <0.01
  -No (n = 321) 143 (44.5%) 1    
Prostration      
  -Yes (n = 95) 18 (18.9%) 2.3[1.2-4.3] <0.01 3.6[0.0-40.8] 0.3
  -No (n = 323) 30 (9.3%) 1    
Neurological symptomsf      
  -Yes (n = 95) 39 (41.0%) 3.2[1.9-5.2] <0.01 3.4[1.9-6.3] <0.01
  -No (n = 323) 60 (18.6%) 1    
Anaemia      
  -Yes (n = 95) 86 (90.5%) 3.2[1.3-7.7] <0.01 3.3[1.6-7.9] <0.01
  -No (n = 323) 269 (83.3%) 1    
Severe anaemia      
  -Yes (n = 95) 14 (14.7%) 1.7[0.8-3.3] <0.13 1.8[0.8-4.2] 0.1
  -No (n = 323) 30 (9.3%) 1    
BCS ≤ 2      
  -Yes (n = 95) 2 (2.1%) --- ---   
  -No (n = 323) 0 (0.0%° -- ---   
Thrombopenia      
  -Yes (n = 95) 80 (84.2%) 19.6[10.6-36.2] <0.01 2.6[1.3-5.3] <0.01
  -No (n = 323) 69 (21.4%) 1    
VOCg      
  -Yes (n = 95) 2 (2.1%) 0.2[0.02-0.7] <0.01 0.1[0.0-0.5] <0.01
  -No (n = 323) 35 (10.8%) 1    
  1. a: crude odds ratio; b: 95% confidence interval; c: adjusted odds ratio d: malaria infected patients; e: non infected patients;
  2. f: see detailed symptoms in Table 1, g : vaso-occlusive crisis in patients with sickle cell disease.