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Table 3 Logistic regression analysis of factors associated with risk of complicated malaria

From: Complicated malaria and other severe febrile illness in a pediatric ward in Libreville, Gabon

Variables

Malaria

ORa[95%CI]b

p

aORc[95%CI]

p

 

Prevalence

    

Age

     

  - ≥ 5 years (n = 86)

32 (37.2%)

2.6[1.5-4.3]

<0.01

2.5[1.3-4.7]

<0.01

  - < 5 years (n = 332)

63 (19.0%)

1

   

Bed net

     

  - users (n = 276)

47 (17.0%)

0.4[0.2-0.6]

<0.01

0.4[0.2-0.7]

<0.01

  - non users (n = 129

44 (34.1%)

1

   

Drug intake

     

  -Yesd (n = 95)

41 (43.2%)

0.5[0.3-0.8]

<0.01

1.3[0.8-2.3]

0.3

  -Nod (n = 323)

93 (28.8%)

1

   

Pallor

     

  -Yes (n = 95)

66 (69.5%)

2.8[1.7-4.0]

<0.01

2.9[1.7-5.2]

<0.01

  -No (n = 321)

143 (44.5%)

1

   

Prostration

     

  -Yes (n = 95)

18 (18.9%)

2.3[1.2-4.3]

<0.01

3.6[0.0-40.8]

0.3

  -No (n = 323)

30 (9.3%)

1

   

Neurological symptomsf

     

  -Yes (n = 95)

39 (41.0%)

3.2[1.9-5.2]

<0.01

3.4[1.9-6.3]

<0.01

  -No (n = 323)

60 (18.6%)

1

   

Anaemia

     

  -Yes (n = 95)

86 (90.5%)

3.2[1.3-7.7]

<0.01

3.3[1.6-7.9]

<0.01

  -No (n = 323)

269 (83.3%)

1

   

Severe anaemia

     

  -Yes (n = 95)

14 (14.7%)

1.7[0.8-3.3]

<0.13

1.8[0.8-4.2]

0.1

  -No (n = 323)

30 (9.3%)

1

   

BCS ≤ 2

     

  -Yes (n = 95)

2 (2.1%)

---

---

  

  -No (n = 323)

0 (0.0%°

--

---

  

Thrombopenia

     

  -Yes (n = 95)

80 (84.2%)

19.6[10.6-36.2]

<0.01

2.6[1.3-5.3]

<0.01

  -No (n = 323)

69 (21.4%)

1

   

VOCg

     

  -Yes (n = 95)

2 (2.1%)

0.2[0.02-0.7]

<0.01

0.1[0.0-0.5]

<0.01

  -No (n = 323)

35 (10.8%)

1

   
  1. a: crude odds ratio; b: 95% confidence interval; c: adjusted odds ratio d: malaria infected patients; e: non infected patients;
  2. f: see detailed symptoms in Table 1, g : vaso-occlusive crisis in patients with sickle cell disease.