Table 1 Comparisons of demographic and clinical data between the groups of different HD access related ESBL-Kp bacteremia
Source of infection | HD catheter | Fistula | Graft | ALL |
|---|---|---|---|---|
Case No | 42 | 7 | 8 | 57 |
Male (%) | 33 (78.6) | 6 (85.7) | 6 (75) | 45 (78.9) |
Age, years | 64.8 ± 10.0 | 61 ± 10.5 | 65.1 ± 7.8 | 64.4 ± 9.5 |
Patients aged >65 years (%) | 24 (57.1) | 3 (42.9) | 5 (62.5) | 32 (56.1) |
Admission for infectious diseases (%) | 23 (54.8) | 5 (71.4) | 6 (75) | 34 (59.6) |
Significant underlying diseases (%) | ||||
Diabetes mellitus | 15 (35.7) | 4 (57.1) | 7 (87.5) | 26 (45.6) |
Liver cirrhosis | 5 (11.9) | 1 (14.3) | 2 (25) | 8 (14) |
Congestive heart failure | 10 (23.8) | 3 (42.9) | 5 (62.5) | 18 (31.6) |
Malignancy | 4(9.5) | 1 (14.3) | 1 (12.5) | 5 (8.8) |
Comorbid conditions (%) | ||||
Poor nutritiona | 42 (100) | 7 (100) | 8 (100) | 57 (100) |
Prior antibiotic useb | 37 (88.1) | 6 (85.7) | 7 (87.5) | 50 (87.7) |
Previous severe illnessc | 35 (83.3) | 6 (85.7) | 6 (75) | 47 (82.5) |
Prolonged (>30 days) hospitalization | 33 (78.6) | 5 (71.4) | 6 (75) | 44 (77.2) |
Prior use of 3rd-generation cephalosporin | 27 (64.3) | 5 (71.4) | 6 (75) | 38 (66.7) |
ICU stay at or after the onset of bacteremia | 20 (47.6) | 4 (57.1) | 5 (62.5) | 29 (50.9) |
Pitt bacteremia score | 5.29 ± 1.67 | 5 ± 1.73 | 6.38 ± 2.26 | 5.4 ± 1.78 |
ABx after onset of bacteremia d | ||||
Effective ABx within 5 days (%) | 15 (35.7) | 3 (42.9) | 3 (37.5) | 21 (36.8) |
Use flomoxef/IMP /MEP as effective ABx(%) | 19(45)/13(31)/ 10(24) | 4(57)/3(43)/ none | 6 (75)/none/ 2(25) | 29(51)/16(28)/ 12(21) |
Mortality (%) | 27 (64.3) | 3 (42.9) | 6 (75) | 36 (63.2) |