Skip to main content

Table 3 Performance of smears and PS-PCR analyses, and their combination, in the diagnosis of ATL

From: Polymorphism-specific PCR enhances the diagnostic performance of American tegumentary leishmaniasis and allows the rapid identification of Leishmania species from Argentina

Assay Sensitivity (%) Specificity (%) PPV (%) NPV (%)
Smear 70.5 100 99.9 73.6
PS-PCR 81 84.2 86.2 78.5
Smear + PS-PCR 97.61 83.3 87.9 91
  1. PPV = positive predictive values; NPV = negative predictive values, estimated applying the theorem of Bayes. The positive and negative PCR controls and the results from healthy individuals from non-endemic areas were not included in the calculations.1The differences between proportions were statistically significant (P = 0.0018) when the Smear + PS-PCR were compared against these tests alone.