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Table 1 Antimicrobial susceptibility of S. pyogenes as classified by CLSI and EUCAST §

From: Does the adoption of EUCAST susceptibility breakpoints affect the selection of antimicrobials to treat acute community-acquired respiratory tract infections?

Antimicrobial agenta(n° of strains) CLSI susceptibility breakpoint (mg/L) EUCAST susceptibility breakpoint (mg/L) CLSI %S EUCAST %S Type of discrepancyb
Penicillin (934) 0.12 0.25 99.9 100 -
Azithromycin (22.884) 0.5 0.25 91.7 91.2 -
Clindamycin (10.994) 0.25 0.5 96.6 96.7 -
Levofloxacin (26.775) 2 1 99.0 93.1 minor
Vancomycin (10.728) 1 2 100 100 -
Tetracycline (2.413) 2 1 83.9 83.7 -
  1. § CLSI [11] and EUCAST [13].
  2. AFor Erythromycin, Clarithromycin, Linezolid and Daptomycin CLSI and EUCAST suggested the same susceptibility breakpoints.
  3. b Discrepancy as defined in the materials and methods section.