Table 2 Specific symptoms and responses to therapy of the 13 patients with probable late Lyme disease
From: Probable late lyme disease: a variant manifestation of untreated Borrelia burgdorferi infection
Patient | Exposure History | Presenting Symptom/signs | Duration Symptoms | Treatment | Outcome |
|---|---|---|---|---|---|
1 | Non-diagnostic skin lesion not treated. (See figure 2) | Arthralgias, neck stiffness, fatigue; Olecranon bursitis | 12 months | Doxycycline 4 weeks | All symptoms resolved. No Relapse |
2 | Unknown | Arthralgias: hip; Headache | 5 years | Doxycycline 7 weeks | 80% Improved. No relapse |
3 | Tick bite with cellulitis Rx with cephalexin | Arthralgias: jaw, arm; Fatigue, memory problems | 3 months | Amoxicillin 4 weeks | 95% improved. No relapse |
4 | Unknown | Back pain | 18 months | Unknown | Unknown |
5 | Spider bite, Rx with erythromycin | Arthralgias, Poor memory; Night sweats | 15 months | Ceftriaxone 3 weeks; Amoxicillin 4 weeks | Improved. Relapsed |
6 | Unknown | Memory loss w/normal CSF dysthesias | 6 months | Doxycycline 12 weeks | No improvement. |
7 | Viral symptoms with rash Rx with 5 day Zithromax | Arthralgia; Fatigue | 6 months | Doxycycline 3 weeks | 80% improved. Relapsed |
8 | Unknown | Leg myalgia | 12 months | Doxycycline 12 weeks | No clinically significant improvement |
9 | Unknown | Arthralgias; Olecranon bursitis | 12 months | Doxycycline 6 weeks | Marked improvement |
10 | Remote untreated EM 25 years prior | Memory loss | 12 months | Doxycycline 4 weeks | No improvement |
11 | Viral like illness | Arthralgias; Olecranon bursitis, Edema | 7 months | Doxycycline 3 weeks | Complete response. Relapsed |
12 | Round rash, no treatment | Arthralgias | 30 months | Doxycycline 4 weeks | Improvement. Relapsed |
13 | Unknown | Fatigue, arthralgias, vertigo | 18 months | Doxycycline 8 weeks | 50% improved. No relapse |