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Table 1 Demographic and clinical characteristics of patients included in this retrospective chart review*

From: Probable late lyme disease: a variant manifestation of untreated Borrelia burgdorferi infection

Characteristics

Confirmed Late (n=23)

Probable Late (n=13)

PLS (n=36)

Other diagnosis (n=35)

No specific diagnosis (n=128)

Demographics

     

Age at illness onset

49.1 (44.9-65.3)

56.6 (50-67)

46.6 (35.5-52.5)

55.4 (36.5-61.6)

42.2 (32.1-53.0)

Male Sex

14/23 (61%)

6/13 (46%)

19/36 (53%)

14/35 (40%)

43/128 (34%)

Illness duration (weeks)

52 (9-130)

63 (52-152)

127 (30-270)

52 (25-216)

78 (40-204)

Symptoms

     

Widespread musculoskeletal pain

2/23 (9%)

11/13 (85%)

36/36 (100%)

17/35 (49%)

112/128 (88%)

Fatigue

0/23 (0%)

8/13 (62%)

32/36 (89%)

15/35 (43%)

96/128 (75%)

Cognitive complaints

0/23 (0%)

6/13 (46%)

19/36 (53%)

8/35 (23%)

67/128 (52%)

Signs

     

Patient reported rash in absence of physician diagnosis of EM

1/23 (4%)

5/13 (38%)

1/36 (3%)

5/35 (14%)

33/128 (26%)

Physician documented EM

1/23 (4%)

0/13 (0%)

26/36 (72%)

4/35 (11%)

1/128 (1%)

Other physician documented objective findings

21/23 (91%)

0/13 (0%)

9/36 (25%)

2/35 (6%)

11/128 (9%)

Serology

     

% ELISA positive ( >.9)

17/18 (94%)

11/11 (100%)

18/28 (64%)

6/23 (26%)

6/104 (6%)

Median ELISA among those (+)

3.5

2.0

1.8

1.75

1.4

% IgM immunoblot (+)

14/22 (64%)

2/11 (18%)

14/31 (45%)

4/28 (14%)

32/109 (29%)

Treatment

     

Non-recommended antibiotic

8/23 (35%)

4/13 (31%)

14/36 (39%)

6/35 (17%)

43/128 (34%)

Steroid

3/23 (13%)

2/13 (15%)

9/36 (25%)

5/35 (14%)

19/128 (15%)

  1. *no. (%) for dichotomous variables and median (IQR) for continuous variables.