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Table 2 Comparison of tuberculin skin test (TST), QuantiFERON-TB Gold (QFG), and T-SPOT.TB in all the patients, in patients with past or current tuberculosis (TB) or previous positive tuberculin skin test (TST) and in patients with no past or current TB nor treatment for LTBI with and without TB contact

From: Contribution of Interferon gamma release assays testing to the diagnosis of latent tuberculosis infection in HIV-infected patients: A comparison of QuantiFERON-TB Gold In Tube, T-SPOT.TB and tuberculin skin test

Test Patients Results of Test
   Positive Borderline Negative Indeterminate or invalid
TST All patients (n = 373) 46 (12.3) - 299 (80.2) 28 (7.5)
  Patients with past or current TB or positive TST (n = 71) 26 (36.6) - 42 (59.2) 3 (4.2)
  Patients with no past or current TB nor positive TST without TB contact (n = 209) 7 (3.3)   188 (90.0) 14 (6.7)
  Patients with no past or current TB nor positive TST with TB contact (n = 93) 13 (14.0) - 69 (74.2) 11 (11.8)
QFG All patients (n = 373) 28 (7.5) - 335 (89.8) 10 (2.7)
  Patients with past or current TB or positive TST (n = 71) 15 (21.1) - 56 (78.9) 0 (0)
  Patients with no past or current TB nor positive TST without TB contact (n = 209) 6 (2.9)   198 (94.7) 5 (2.4)
  Patients with no past or current TB nor positive TST with TB contact (n = 93) 7 (7.5) - 81 (87.1) 5 (2.4)
T-SPOT.TB (Mc) All patients (n = 373) 69 (18.5) - 278 (74.5) 26 (7.0)
  Patients with past or current TB or positive TST (n = 71) 27 (38.0) - 40 (56.3) 4 (5.6)
  Patients with no past or current TB nor positive TST with TB contact (n = 209) 28 (13.4)   166 (74.4) 15 (7.2)
  Patients with no past or current TB nor positive TST with TB contact (n = 93) 14 (15.1) - 72 (77.4) 7 (7.5)
T-SPOT.TB (FDAc) All patients (n = 373) 50 (13.4) 27 (7.2) 270 (72.4) 26 (7.0)
  Patients with past or current TB or positive TST (n = 71) 22 (31.0) 7 (9.9) 38 (53.5) 4 (5.6)
  Patients with no past or current TB nor positive TST without TB contact (n = 209) 20 (9.6) 12 (5.7) 162 (77.5) 15 (7.2)
  Patients with no past or current TB nor positive TST with TB contact (n = 93) 8 (8.6) 8 (8.6) 70 (72.9) 7 (7.5)
  1. NOTE. Data are no (%) of patients unless otherwise indicated.
  2. Mc: Manufacturer’s interpretation criteria; FDAc: Food and Drug Agency’s interpretation criteria.