Table 3 Changes in haemoglobin level, white blood cell and CD4 count during treatment among pulmonary tuberculosis patients with (n = 197) or without (n = 1008) diabetes
Patients without diabetes | Patients with diabetes | ||
|---|---|---|---|
(n = 2008) | (n = 197) | ||
Mean (95% CI) | Mean (95% CI) | P | |
Haemoglobin, g pr. dL | |||
Baseline | 10.8 (10.6; 10.9) | 10.7 (10.4; 11.0) | |
2 months | 12.3 (12.2; 12.5) | 11.7 (11.4; 12.0) | |
Increase | 1.6 (1.4; 1.7) | 1.0 (0.7; 1.3) | |
Difference | 0.6 (0.3; 0.9) | < 0.001 | |
5 months | 13.0 (12.8; 13.1) | 12.4 (12.1; 12.7) | |
Increase | 2.2 (2.1; 2.3) | 1.7 (1.4; 2.0) | |
Difference | 0.5 (0.2; 0.9) | 0.004 | |
White blood cell count (total), 109 cells pr. L | |||
Baseline | 6.4 (6.3; 6.6) | 6.8 (6.5; 7.1) | |
2 months | 4.7 (4.6; 4.8) | 5.0 (4.7; 5.3) | |
Increase | −1.7 (−1.9; -1.6) | −1.7 (−2.1; -1.4) | |
Difference | 0.02 (−0.3; 0.4) | 0.918 | |
5 months | 4.3 (4.1; 4.4) | 4.6 (4.3; 4.9) | |
Increase | −2.2 (−2.3; -2.0) | −2.2 (−2.5; -1.8) | |
Difference | −0.03 (−0.4; 0.3) | 0.889 | |
Neutrophil granulocytes, 109 cells pr. L | |||
Baseline | 4.1 (4.0; 4.2) | 4.6 (4.4; 4.8) | |
2 months | 2.3 (2.2; 2.4) | 2.6 (2.4; 2.8) | |
Increase | −1.8 (−2.0; -1.7) | −2.0 (−2.2; -1.7) | |
Difference | 0.1 (−0.2; 0.4) | 0.493 | |
5 months | 1.8 (1.7; 2.0) | 2.2 (2.0; 2.5) | |
Increase | −2.3 (−2.4; -2.1) | −2.3 (−2.6; -2.1) | |
Difference | 0.1 (−0.2; 0.4) | 0.658 | |
CD4 count, cells pr. μL | |||
Baseline | 425.9 (408.9; 442.8) | 409.2 (370.6; 447.8) | |
2 months | 477.5 (459.9; 495.2) | 435.1 (393.7; 476.5) | |
Increase | 51.7 (29.7; 73.6) | 25.9 (−25.0; 76.8) | |
Difference | 25.7 (−29.7; 81.2) | 0.362 | |
5 months | 436.2 (417.7; 454.6) | 396.6 (353.7; 439.6) | |
Increase | 10.3 (−12.3; 32.9) | −12.5 (−64.6; 39.6) | |
Difference | 22.8 (−33.9; 79.6) | 0.431 |