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Table 2 Changes in anthropometric measurements and grip strength during TB treatment among TB patients with (n = 197) or without (n = 1008) diabetes

From: The role of diabetes co-morbidity for tuberculosis treatment outcomes: a prospective cohort study from Mwanza, Tanzania

  Patients without diabetes Patients with diabetes   
  (n = 2008) (n = 197)   
  Mean (95% CI) Mean (95% CI) P  
Weight, kg     
 Baseline 51.8 (51.3; 52.3) 53.3 (52.1; 54.5)   
 2 months 54.8 (54.3; 55.3) 55.1 (53.9; 56.3)   
  Increase 3.0 (2.7; 3.3) 1.7 (1.1; 2.4)   
  Difference 1.3 (0.5; 2.0)   0.001  
 5 months 57.1 (56.6; 57.7) 57.7 (56.4; 58.9)   
  Increase 5.3 (5.0; 5.6) 4.3 (3.7; 5.0)   
  Difference 1.0 (0.3; 1.7)   0.007  
BMI, kg/m2     
 Baseline 18.7 (18.6; 18.9) 19.3 (18.9; 19.7)   
 2 months 19.8 (19.6; 20.0) 19.9 (19.5; 20.3)   
  Increase 1.1 (1.0; 1.2) 0.6 (0.4; 0.9)   
  Difference 0.4 (0.2; 0.7)   0.001  
 5 months 20.7 (20.5; 20.9) 20.9 (20.4; 21.3)   
  Increase 1.9 (1.8; 2.0) 1.6 (1.3; 1.8)   
  Difference 0.3 (0.1; 0.6)   0.012  
Waist circumference, cm     
 Baseline 72.1 (71.7; 72.5) 73.7 (72.8; 74.7)   
 2 months 74.5 (74.0; 74.9) 75.8 (74.8; 76.9)   
  Increase 2.4 (2.1; 2.7) 2.1 (1.4; 2.8)   
  Difference 0.3 (−0.5; 1.0)   0.512  
 5 months 76.3 (75.9; 76.8) 77.8 (76.8; 78.8)   
  Increase 4.2 (3.9; 4.5) 4.1 (3.3; 4.8)   
  Difference 0.2 (−0.6; 1.0)   0.697  
AMA, mm2     
 Baseline 34.6 (34.0; 35.1) 35.6 (34.3; 37.0)   
 2 months 37.2 (36.6; 37.8) 37.4 (36.0; 38.7)   
  Increase 2.7 (2.2; 3.1) 1.7 (0.7; 2.7)   
  Difference 0.9 (−0.2; 2.0)   0.100  
 5 months 40.7 (40.1; 41.4) 41.0 (39.6; 42.4)   
  Increase 6.2 (5.7; 6.6) 5.4 (4.4; 6.4)   
  Difference 0.8 (−0.3; 1.9)   0.164  
AFA, mm2     
 Baseline 8.1 (7.8; 8.4) 8.3 (7.6; 9.0)   
 2 months 9.2 (8.9; 9.5) 9.0 (8.3; 9.8)   
  Increase 1.1 (0.9; 1.4) 0.8 (0.1; 1.4)   
  Difference 0.4 (−0.3; 1.0)   0.297  
 5 months 10.4 (10.1; 10.8) 10.4 (9.6; 11.2)   
  Increase 2.3 (2.1; 2.6) 2.1 (1.5; 2.8)   
  Difference 0.2 (−0.5; 0.9)   0.524  
Grip strength, kg     
 Baseline 25.8 (25.3; 26.3) 25.2 (24.2; 26.2)   
 2 months 27.6 (27.2; 28.1) 26.8 (25.7; 27.9)   
  Increase 1.8 (1.5; 2,2) 1.6 (0.7; 2.4)   
  Difference 0.2 (−0.7; 1.2)   0.610  
 5 months 30.5 (30.0; 30.9) 29.6 (28.5; 30.7)   
  Increase 4.7 (4.3; 5.0) 4.4 (3.5; 5.2)   
  Difference 0.3 (−0.7; 1.2)   0.550  
  1. Data are mean (95% confidence interval) based on multilevel mixed-effects linear regression, adjusted for age, sex, HIV status, alpha-1 glycoprotein, smoking habits, alcohol intake, and nutritional intervention.
  2. TB: pulmonary tuberculosis, BMI: body mass index, AMA: arm muscle area, AFA: arm fat area.