Table 2 Baseline Demographic and Medical Characteristics for CE Population: Switched vs. Not Switched from IV to Oral Therapy
Characteristic | Switched (IV to oral) | No Switch (IV only) | ||||
|---|---|---|---|---|---|---|
Tigecycline N = 124 | Levofloxacin N = 137 | P-value | Tigecycline N = 14 | Levofloxacin N = 19 | P-value | |
Age, yrs, mean ± SD | 55.2 ±16.4 | 54.0 ± 20.4 | 0.613 | 60.1 ± 18.1 | 63.1 ± 17.2 | 0.634 |
Male, n (%) | 64 (51.6) | 83 (60.6) | 0.145 | 9 (64.3) | 13 (68.4) | 0.803 |
Ethnic origin, n (%) | 0.189 | 0.620 | ||||
White | 80 (64.5) | 87 (63.5) | 9 (64.3) | 9 (47.4) | ||
Hispanic | 29 (23.4) | 34 (24.8) | 5 (35.7) | 7 (36.8) | ||
Black | 14 (11.3) | 9 (6.6) | 0 | 1 (5.3) | ||
Asian | 0 | 4 (2.9) | 0 | 1 (5.3) | ||
Other | 1 (0.8) | 3 (2.2) | 0 | 1 (5.3) | ||
Fine Score, n (%) | 0.452 | 0.816 | ||||
I | 28 (22.6) | 41 (29.9) | 3 (21.4) | 2 (10.5) | ||
II | 43 (34.7) | 42 (30.7) | 1 (7.1) | 1 (5.3) | ||
III | 33 (26.6) | 29 (21.2) | 5 (35.7) | 7 (36.8) | ||
IV | 20 (16.1) | 25 (18.2) | 5 (35.7) | 9 (47.4) | ||
Prior antibiotic failure, n (%) | 2 (1.6) | 4 (3.0) | 0.471 | 0 | 1 (5.3) | 0.383 |
Therapy duration, days, mean ± SD | 11.39 ± 2.0 | 11.26 ± 2.0 | 0.599 | 6.7 ± 3.1 | 6.3 ± 3.7 | 0.746 |
Presence of multilobar infiltrates, n (%) | 32 (25.8) | 22 (16.1) | - | 7 (50.0) | 7 (36.8) | - |
Presence of altered mental status, n (%) | 2 (1.6) | 5 (3.6) | - | 0 | 1 (5.3) | - |