Value of soluble TREM-1, procalcitonin, and C-reactive protein serum levels as biomarkers for detecting bacteremia among sepsis patients with new fever in intensive care units: a prospective cohort study

Table 2 Area under ROC curve as a means of differentiating sepsis from SIRS

variable	AUC	Std. Error	P value	Asymptotic 95% Confidence Interval		Cut	sen	spe	PPV	NPV	PLR	NLR	YI
				Lower limit	Upper limit	point
sTREM-1	0.868	0.036	<0.001	0.798	0.938	108.9	0.83	0.81	0.86	0.65	2.9	0.31	0.64
PCT	0.729	0.047	<0.001	0.637	0.821	2.1	0.55	0.83	0.82	0.42	2.14	0.51	0.38
CRP	0.675	0.049	0.001	0.578	0.771	16.5	0.35	0.98	0.96	0.35	2.85	0.76	0.33
APACHEII score	0.745	0.045	<0.001	0.656	0.833	19.5	0.49	0.89	0.86	0.4	3.49	0.62	0.39

PPV Positive Predictive Value; NPV Negtive Predictive Value; PLR Positive Likelihood Ratio; NLR Negative Likelihood Ratio; YI Youden Index.

ISSN: 1471-2334