Table 4 Multivariate analyses of the association between high- and low-risk human papillomavirus infections and selected subjects’ characteristics
Any HR HPV vs. negative (n = 3074) | Only LR HPV vs. negative (n = 2628) | |||||
|---|---|---|---|---|---|---|
No. tested | Adjusted model1 | No. tested | Adjusted model1 | |||
POR | 95% CI | POR | 95% CI | |||
Age group (years) | ||||||
18 | 302 | 2.3 | 1.3–4.1 | 234 | 0.7 | 0.2–2.3 |
19 | 327 | 2.7 | 1.5–4.7 | 250 | 1.4 | 0.5–4.0 |
20–21 | 440 | 2.6 | 1.5–4.5 | 333 | 0.9 | 0.3–2.6 |
22–25 | 449 | 2.2 | 1.3–3.8 | 356 | 1.6 | 0.6–4.2 |
26–35 | 312 | 1.3 | 0.7–2.3 | 272 | 0.7 | 0.2–2.3 |
36–45 | 325 | 0.9 | 0.5–1.7 | 296 | 0.1 | 0.0–0.8 |
46–55 | 474 | 0.8 | 0.4–1.4 | 456 | 1.1 | 0.4–2.8 |
56–65 | 445 | 1 | reference | 431 | 1 | reference |
P-value for trend | <0.001 | 0.8 | ||||
Residential area | ||||||
Rural | 324 | 1 | reference | 286 | 1 | reference |
Suburban | 383 | 1.3 | 0.8–2.1 | 332 | 1.5 | 0.5–4.7 |
Urban | 2362 | 1.5 | 1.0–2.2 | 2006 | 1.5 | 0.6–4.1 |
Unknown | 5 | - | - | 4 | - | - |
P-value for trend | 0.03 | 0.4 | ||||
Country of birth | ||||||
Spain | 2811 | 1 | reference | 2436 | 1 | reference |
Other countries | 263 | 2.0 | 1.4–2.8 | 192 | 0.6 | 0.2–1.6 |
Marital status | ||||||
Married | 1143 | 1 | reference | 1102 | 1 | reference |
Single | 1214 | 2.1 | 1.4–3.2 | 943 | 2.8 | 1.1–7.1 |
Cohabiting | 533 | 1.7 | 1.1–2.7 | 428 | 2.3 | 0.9–5.9 |
Divorced/ Separated | 125 | 2.7 | 1.5–4.7 | 101 | 0.8 | 0.2–3.6 |
Widowed | 59 | 4.0 | 1.7–9.3 | 54 | 3.4 | 0.9–13.1 |
Level of educational attainment | ||||||
No formal education | 177 | 1 | reference | 152 | 1 | reference |
Primary completed | 640 | 0.9 | 0.5–1.5 | 564 | 2.2 | 0.3–18.5 |
Secondary completed | 1241 | 0.7 | 0.4–1.2 | 1041 | 5.6 | 0.7–42.4 |
University or higher | 1013 | 0.6 | 0.3–1.0 | 868 | 3.8 | 0.5–30.1 |
Unknown | 3 | - | - | 3 | - | - |
P-value for trend | 0.003 | 0.2 | ||||
Tobacco smoking status | ||||||
Never smoked | 1566 | 1 | reference | 1405 | 1 | reference |
Ex-smoker | 426 | 0.9 | 0.6–1.3 | 395 | 1.4 | 0.7–2.8 |
Current smoker | 1081 | 1.6 | 1.3–2.1 | 827 | 1.2 | 0.7–2.0 |
Unknown | 1 | - | - | 1 | - | - |
P-value for trend | <0.001 | 0.5 | ||||
Ever use of condoms | ||||||
Never used | 630 | 1 | reference | 585 | 1 | reference |
Ex or current user | 2444 | 0.9 | 0.7–1.3 | 2043 | 0.5 | 0.3–1.0 |
Systematic condom use in last 12 months* | ||||||
No | 1902 | 1 | reference | 1633 | 1 | reference |
Yes | 1001 | 0.8 | 0.6–1.0 | 835 | 1.0 | 0.6–1.7 |
Unknown | 11 | - | - | 12 | - | - |
Lifetime number of sexual partners | ||||||
1 | 1534 | 1 | reference | 1447 | 1 | reference |
2 | 564 | 1.6 | 1.2–2.2 | 487 | 1.2 | 0.6–2.4 |
3 | 383 | 3.5 | 2.6–4.9 | 289 | 2.6 | 1.3–5.2 |
≥4 | 581 | 4.4 | 3.3–5.9 | 396 | 3.0 | 1.6–5.6 |
Unknown | 12 | - | - | 9 | - | - |
P-value for trend | <0.001 | <0.001 | ||||
Age at first sexual intercourse (years) | ||||||
≤14 | 121 | 0.7 | 0.3–1.8 | 88 | 0.2 | 0.0–1.2 |
15–16 | 671 | 0.8 | 0.3–1.9 | 507 | 0.2 | 0.1–0.8 |
17–18 | 1061 | 0.9 | 0.4–2.0 | 898 | 0.5 | 0.1–1.6 |
19–20 | 481 | 1.0 | 0.4–2.5 | 434 | 0.5 | 0.1–1.8 |
21–25 | 584 | 1.3 | 0.6–3.2 | 548 | 0.6 | 0.2–1.9 |
≥26 | 141 | 1 | reference | 138 | 1 | reference |
Unknown | 15 | - | - | 15 | - | - |
P-value for trend | 0.02 | 0.01 | ||||
Current partner circumcised | ||||||
No | 2311 | 1 | reference | 1989 | 1 | reference |
Yes | 359 | 0.7 | 0.5–1.0 | 319 | 1.2 | 0.6–2.4 |
Unknown | 404 | - | - | 320 | - | - |
History of genital warts | ||||||
No | 2991 | 1 | reference | 2576 | 1 | reference |
Yes | 78 | 2.9 | 1.7–4.9 | 46 | 6.6 | 2.8–15.4 |
Unknown | 5 | - | - | 6 | - | - |