Factors associated with non-adherence to Artemisinin-based combination therapy (ACT) to malaria in a rural population from holoendemic region of western Kenya

Table 3 Demographic factors associated with ACT adherence in Southeast Alego location

Demographic factors		Adhered	Did not adhere	P-value^a	OR	95 % CI	P-value^b
Age	<13 years	81 (57.9 %)	69 (43.9 %)	0.011	0.571	0.360-0.905	0.017
	≥13 years	59 (42.1 %)	88 (56.1 %)		1.00 (reference category)
Gender	Male	62 (44.3 %)	79 (50.3 %)	0.178	1.274	0.807-2.013	0.229
	Female	78 (55.7 %)	78 (49.7 %)		1.00 (reference category)
Marital status	Married	30 (21.4 %)	42 (26.1 %)	0.220	1.540	0.872-2.720	0.137
	Widowed	11 (7.9 %)	11 (7.0 %)		1.352	0.551-3.319	0.510
	Separated	1 (0.7 %)	3 (1.9 %)		3.380	0.344-33.234	0.296
	Single	18 (2.9 %)	31 (19.7 %)		1.779	0.922-3.434	0.086
	Underage	80 (57.1 %)	71 (45.2 %)		1.00 (reference category)
HH head	Wife	34 (24.3 %)	48 (30.6 %)	0.140	1.373	0.821-2.296	0.227
	Husband	106 (75.7 %)	109 (69.4 %)		1.00 (reference category)
HH size	1-2	5 (3.6 %)	10 (6.4 %)	0.121	2.339	0.757-7.229	0.140
	3-5	66 (47.1 %)	88 (56.1 %)		1.559	0.975-2.500	0.065
	≥6	69 (49.3 %)	58 (36.9 %)		1.00 (reference category)

Legend: HH- Household, ACT- Artemisinin-based combined therapies. From the results, age significantly affected adherence in the study population (P = 0.011). ^aStatistical significance determined by Chi-square tests. P-value is significant at P ≤ 0.050. ^bStatistical significance determined by logistic regression tests.

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