Figure 4
From: The role of TLR2 in the host response to pneumococcal pneumonia in absence of the spleen
Lung pathology induced by serotype 3 S. pneumoniae . Representative slides of lung tissue obtained at 24 hours after infection with 7*104 CFU S. pneumoniae (ATCC), in WT mice (panel A) and TLR2KO mice (panel B).Representative slides of lung tissue obtained at 24 hours after infection with 7*104 CFU S. pneumoniae (ATCC), in WT mice (panel A) and TLR2KO mice (panel B).Haematoxylin and eosin staining. Magnification 10x. Insets: representative slides of lung Ly-6 G staining (brown), showing influx of neutrophils. Findings are quantified by total pathology scores (total lung inflammation scores, TLIS) in panel C, and scores of pulmonary Ly-6 G in panel D, at 24 hours after induction of pneumococcal pneumonia. Data are expressed as means ± SE (3–7 mice per group). ** indicate p = 0,0012.