|
Characteristics
|
Conventional Bacteria (N = 163 )
|
Atypical Agent (N = 151)
|
Virus (N = 41)
|
Mixed Infection (N = 35)
|
Pvalue†
|
|---|
|
Age, years, mean (SD)
|
68.9 (18.3)
|
47.5 (18.3)
|
66.1 (17.5)
|
61.9 (22.9)
|
<0.0001
|
|
Female
|
72 (44.2)
|
51 (36.8)
|
19 (46.3)
|
9 (25.7)
|
0.07
|
|
Immunized against influenza
|
83 (53.6)
|
32 (22.2)
|
32 (82.1)
|
19 (54.3)
|
<0.0001
|
|
Immunized against pneumococcal infection
|
10 (6.8)
|
4 (2.8)
|
2 (5.1)
|
1 (2.9)
|
0.4
|
|
Number of comorbid conditions
| | | | |
0.002
|
|
0
|
96 (60)
|
120 (81.6)
|
24 (60)
|
21 (60)
| |
|
1
|
44 (27.5)
|
20 (13.6)
|
13 (32.5)
|
11 (31.4)
| |
|
>1
|
20 (12.5)
|
7 (4.8)
|
3 (7.5)
|
3 (8.6)
| |
|
Underlying diseases
| | | | | |
|
Neoplastic disease
|
10 (6.1)
|
4 (2.7)
|
0 (0)
|
3 (8.6)
|
0.2
|
|
Liver disease
|
1 (0.6)
|
2 (1.3)
|
0 (0)
|
3 (8.6)
|
0.005
|
|
Congestive heart failure
|
8 (4.9)
|
4 (2.7)
|
0 (0)
|
0 (0)
|
0.2
|
|
Cerebrovascular disease
|
11 (6.8)
|
2 (1.3)
|
1 (2.4)
|
2 (5.7)
|
0.09
|
|
Renal disease
|
7 (4.3)
|
4 (2.7)
|
1 (2.4)
|
2 (5.7)
|
0.7
|
|
Chronic obstructive pulmonary disease
|
34 (21.1)
|
9 (6.1)
|
11 (27.5)
|
4 (11.4)
|
0.0003
|
|
Diabetes mellitus
|
18 (11.3)
|
13 (8.8)
|
6 (14.6)
|
3 (8.6)
|
0.7
|
|
Severity of illness at diagnostic
| | | | | |
|
CURB-65 score*
| | | | |
<0.0001
|
|
0-1
|
79 (48.5)
|
131 (86.8)
|
29 (70.7)
|
20 (57.1)
| |
|
2
|
47 (28.8)
|
13 (8.6)
|
9 (22)
|
10 (28.6)
| |
|
>2
|
37 (22.7)
|
7 (4.6)
|
3 (7.3)
|
5 (14.3)
| |
|
Bilateral or multilobe radiographic involvement
|
38 (23.5)
|
7 (4.7)
|
0 (0)
|
2 (5.7)
|
<0.0001
|
- SD = standard deviation.
- Data are presented as numbers (percentage) of patients unless otherwise stated. Percentages exclude patients with missing data.
-
* Severity of illness on admission assessed with CURB-65 score (Confusion, Urea nitrogen, Respiratory rate, Blood pressure, age ≥65 year).
-
† The p-value obtained from the Chi-square or Fisher exact test for categorical variables, and Kruskal-Wallis test for continuous variables.
