Characteristics | Conventional Bacteria (N = 163 ) | Atypical Agent (N = 151) | Virus (N = 41) | Mixed Infection (N = 35) | Pvalue† |
---|---|---|---|---|---|
Age, years, mean (SD) | 68.9 (18.3) | 47.5 (18.3) | 66.1 (17.5) | 61.9 (22.9) | <0.0001 |
Female | 72 (44.2) | 51 (36.8) | 19 (46.3) | 9 (25.7) | 0.07 |
Immunized against influenza | 83 (53.6) | 32 (22.2) | 32 (82.1) | 19 (54.3) | <0.0001 |
Immunized against pneumococcal infection | 10 (6.8) | 4 (2.8) | 2 (5.1) | 1 (2.9) | 0.4 |
Number of comorbid conditions | 0.002 | ||||
0 | 96 (60) | 120 (81.6) | 24 (60) | 21 (60) | |
1 | 44 (27.5) | 20 (13.6) | 13 (32.5) | 11 (31.4) | |
>1 | 20 (12.5) | 7 (4.8) | 3 (7.5) | 3 (8.6) | |
Underlying diseases | |||||
Neoplastic disease | 10 (6.1) | 4 (2.7) | 0 (0) | 3 (8.6) | 0.2 |
Liver disease | 1 (0.6) | 2 (1.3) | 0 (0) | 3 (8.6) | 0.005 |
Congestive heart failure | 8 (4.9) | 4 (2.7) | 0 (0) | 0 (0) | 0.2 |
Cerebrovascular disease | 11 (6.8) | 2 (1.3) | 1 (2.4) | 2 (5.7) | 0.09 |
Renal disease | 7 (4.3) | 4 (2.7) | 1 (2.4) | 2 (5.7) | 0.7 |
Chronic obstructive pulmonary disease | 34 (21.1) | 9 (6.1) | 11 (27.5) | 4 (11.4) | 0.0003 |
Diabetes mellitus | 18 (11.3) | 13 (8.8) | 6 (14.6) | 3 (8.6) | 0.7 |
Severity of illness at diagnostic | |||||
CURB-65 score* | <0.0001 | ||||
0-1 | 79 (48.5) | 131 (86.8) | 29 (70.7) | 20 (57.1) | |
2 | 47 (28.8) | 13 (8.6) | 9 (22) | 10 (28.6) | |
>2 | 37 (22.7) | 7 (4.6) | 3 (7.3) | 5 (14.3) | |
Bilateral or multilobe radiographic involvement | 38 (23.5) | 7 (4.7) | 0 (0) | 2 (5.7) | <0.0001 |