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Table 1 Descriptive statistics for laboratory-confirmed influenza outcomes and demographic and clinical variables
| Subjects ages | Subjects ages | Subjects ages | Subjects ages | ||
|---|---|---|---|---|---|
| Total study population | 3–5 years | 6–17 years | 18–49 years | 50–80 years | |
| Variable | (n = 789) | (n = 65) | (n = 197) | (n = 326) | (n = 201) |
| Outcome variables | n (%) | n (%) | n (%) | n (%) | n (%) |
| Influenza diagnosis | |||||
| Positive | 220 (27.9) | 12 (18.5) | 65 (33.0) | 92 (28.2) | 51 (25.4) |
| Negative | 569 (72.1) | 53 (81.5) | 132 (67.0) | 234 (71.8) | 150 (74.6) |
| Influenza type | |||||
| A | 152 (69.1) | 7 (58.3) | 53 (81.5) | 63 (68.5) | 29 (56.9) |
| B | 67 (30.5) | 5 (41.7) | 11 (16.9) | 29 (31.5) | 22 (43.1) |
| AB | 1 (0.5) | 0 (0.0) | 1 (1.5) | 0 (0.0) | 0 (0.0) |
| Influenza A subtypea | |||||
| H1 | 51 (44.0) | 3 (42.9) | 19 (44.2) | 18 (38.3) | 11 (57.9) |
| H3 | 46 (39.7) | 1 (14.3) | 21 (48.8) | 17 (36.2) | 7 (36.8) |
| Unsubtypeable | 19 (16.4) | 3 (42.9) | 3 (7.0) | 12 (25.5) | 1 (5.3) |
| Continuous variables | Value (error)b | Value (error)b | Value (error)b | Value (error)b | Value (error)b |
| Age (years) | 31.2 (19.4) | 4.0 (0.8) | 11.5 (3.6) | 32.0 (9.9) | 56.8 (5.3) |
| Symptom duration (days) | 4.0 (1–90) | 4.0 (1–30) | 3.0 (1–60) | 5.0 (1–60) | 5.0 (1–90) |
| Temperature (°C) | 36.9 (35.6–40.3) | 36.8 (35.9–39.5) | 37.1 (35.6–40.3) | 36.9 (35.9–39.6) | 36.8 (35.6–39.3) |
| Smoking history (pack-years) | 0.0 (0–117.5)c | ––d | ––d | 0.0 (0–51)c | 0.0 (0–117.5) |
| Vaccine to Onset Time (Days)e | 80 (0–365) | 57 (0–198) | 74 (6–348) | 89 (3–342) | 85.4 (8–365) |
| Categorical variables | n (%) | n (%) | n (%) | n (%) | n (%) |
| Enrollment site | |||||
| Outpatient clinic 1 | 284 (36.0) | 6 (9.2) | 61 (31.0) | 137 (42.0) | 80 (39.8) |
| Outpatient clinic 2 | 203 (25.7) | 15 (23.1) | 55 (27.9) | 63 (19.3) | 70 (34.8) |
| Emergency room | 246 (31.2) | 24 (36.9) | 47 (23.9) | 124 (38.0) | 51 (25.4) |
| Pediatric clinic | 56 (7.1) | 20 (30.8) | 34 (17.3) | 2 (0.6) | 0 (0.0) |
| Sex | |||||
| Female | 494 (62.6) | 30 (46.2) | 87 (44.2) | 270 (82.8) | 107 (53.2) |
| Male | 295 (37.4) | 35 (53.8) | 110 (55.8) | 56 (17.2) | 94 (46.8) |
| Acute onset | |||||
| ≤3 days | 273 (34.6) | 30 (46.2) | 99 (50.3) | 100 (30.7) | 44 (21.9) |
| >3 days | 516 (65.4) | 35 (53.8) | 98 (49.8) | 226 (69.3) | 157 (78.1) |
| Fever | |||||
| >38.0°C | 126 (16.0) | 11 (16.9) | 48 (24.4) | 43 (13.2) | 24 (11.9) |
| ≤38.0°C | 663 (84.0) | 54 (83.1) | 149 (75.6) | 283 (86.8) | 177 (88.1) |
| Cough | |||||
| Yes | 736 (93.3) | 63 (96.9) | 176 (89.3) | 299 (91.7) | 198 (98.5) |
| No | 53 (6.7) | 2 (3.1) | 21 (10.7) | 27 (8.3) | 3 (1.5) |
| Sore throat | |||||
| Yes | 630 (79.8) | 33 (50.8) | 170 (86.3) | 278 (85.3) | 149 (74.1) |
| No | 159 (20.2) | 32 (49.2) | 27 (13.7) | 48 (14.7) | 52 (25.9) |
| Shortness of breathe | |||||
| Yes | 346 (43.9) | 20 (30.8) | 73 (37.2) | 166 (50.9) | 87 (43.3) |
| No | 442 (56.0) | 45 (69.2) | 123 (62.8) | 160 (49.1) | 114 (56.7) |
| Nasal congestion | |||||
| Yes | 650 (82.4) | 51 (78.5) | 155 (78.7) | 271 (83.1) | 173 (86.1) |
| No | 139 (17.6) | 14 (21.5) | 42 (21.3) | 55 (16.9) | 28 (13.9) |
| Headache | |||||
| Yes | 619 (78.5) | 31 (47.7) | 134 (68.0) | 286 (87.7) | 168 (83.6) |
| No | 170 (21.5) | 34 (52.3) | 63 (32.8) | 40 (12.3) | 33 (16.4) |
| Conjunctivitise | |||||
| Yes | 44 (5.6) | 6 (9.2) | 4 (2.0) | 16 (4.9) | 18 (9.0) |
| No | 744 (94.3) | 59 (90.8) | 193 (98.0) | 309 (94.8) | 183 (91.0) |
| Body achese | |||||
| Yes | 581 (73.6) | 27 (41.5) | 99 (50.2) | 289 (88.7) | 166 (82.6) |
| No | 207 (26.2) | 37 (56.9) | 98 (49.8) | 37 (11.4) | 35 (17.4) |
| Nausea/vomiting | |||||
| Yes | 347 (44.0) | 19 (29.2) | 107 (54.3) | 155 (47.5) | 66 (32.8) |
| No | 442 (56.0) | 46 (70.8) | 90 (45.7) | 171 (52.5) | 135 (67.2) |
| Smoker | |||||
| Yes | 157 (19.9) | 0 (0.0) | 0 (0.0) | 88 (27.0) | 69 (34.3) |
| No | 632 (80.1) | 65 (100.0) | 197 (100. 0) | 238 (73.0) | 132 (65.7) |
| Vaccinated | |||||
| Yes | 217 (27.5) | 17 (26.2) | 27 (13.7) | 85 (26.1) | 88 (43.8) |
| No | 572 (72.5) | 48 (73.9) | 170 (86.3) | 241 (73.9) | 113 (56.2) |
