Table 1 Characteristics of patients with macrolide-resistant (MR) and macrolide-sensitive (MS) Mycoplasma pneumoniae pneumonia in different age groups
From: Macrolide-resistant Mycoplasma pneumoniae in adolescents with community-acquired pneumonia
Characteristic | Pediatric patients | Adolescent patients | Adult patients | |||
|---|---|---|---|---|---|---|
MR | MS | MR | MS | MR | MS | |
Number | 30 | 15 | 12 | 14 | 7 | 21 |
Age range, years | 1–15 | 1–15 | 16–19 | 16–19 | 20–42 | 28–45 |
Male:female | 16:14 | 7:8 | 6:6 | 8:6 | 4:3 | 11:10 |
Mutation site in 23S rRNA a | ||||||
  A2063G | 26 |  | 10 |  | 6 |  |
  A2064G | 4 |  | 2 |  | 1 |  |
No. of patients prescribed macrolides (%) | 23 (76) | 15 (100) | 9 (75) | 9 (64) | 5 (71) | 6 (28) |
  Clarithromycin | 12 | 10 | 5 | 4 | 2 | 2 |
  Azithromycin | 11 | 5 | 4 | 5 | 3 | 4 |
No. of patients with a change of prescription after macrolide administration (%) | 20 (66) | 0 | 7 (58) | 3 (21) | 3 (42) | 4 (19) |
  Minocycline | 16 |  | 5 | 3 | 1 | 1 |
  Quinolones | 4 b |  | 2 | 0 | 2 | 3 |
Clinical symptoms and laboratory findings at the first examination | ||||||
  Cough | 30 | 15 | 12 | 14 | 7 | 21 |
  Sputum | 23 | 11 | 7 | 8 | 4 | 12 |
  Fever, temperature ≥ 38°C | 26 | 14 | 11 | 13 | 7 | 21 |
  Respiratory rate, > 30/min | 2 | 1 | 0 | 0 | 0 | 0 |
  White Blood Cell, mean (/uL) | 6,410 | 6,520 | 6,810 | 7,010 | 6,620 | 6,710 |
  C-reactive protein, mean (mg/dL) | 2.1 | 1.9 | 3.1 | 3.3 | 3.7 | 3.5 |