Differing clinical characteristics between influenza strains among young healthy adults in the tropics

BMC Infectious Diseases

Table 2 Multivariate analysis comparing clinical features between influenza subtype- positive cases

Influenza H1N1pdm vs H3N2*
Parameters	Adjusted odds ratio (95% Confidence interval)	p value
Blocked nose	0.33 (0.16, 0.72)	0.005
Rash	0.10 (0.02, 0.37)	< 0.001
Eye symptoms	0.47 (0.24, 0.93)	0.03
Injected pharynx	0.45 (0.21, 0.97)	0.04
Fever (≥37.8°C)	0.33 (0.11, 0.99)	0.05
Influenza H1N1pdm vs B*
Parameters	Adjusted odds ratio (95% Confidence interval)	p value
Sore throat	0.44 (0.24, 0.80)	0.007
Fever (≥37.8°C)	0.51 (0.29, 0.92)	0.024
Injected pharynx	0.45 (0.29, 0.72)	< 0.001
Age (per year)	1.25 (1.08, 1.46)	0.003
Dry cough	2.10 (1.25, 3.54)	0.005
Running nose	0.54 (0.34, 0.86)	0.009
Influenza H3N2 vs B*
Parameters	Adjusted odds ratio (95% Confidence interval)	p value
Blocked nose	3.00 (1.24, 7.19)	0.01
Rash	6.88 (1.50, 31.60)	0.01
Age (per year)	1.28 (1.09, 1.51)	0.002
Cough with sputum	0.24 (1.11, 0.51)	< 0.001

*Age, dry cough, wet cough, sore throat, running nose, blocked nose, sore eyes or eye pain, chills/rigors, myalgia/arthralgia, ear symptoms, rash, chest pain, headache, Fever ≥ 37.8°C, Fever ≥ 38.0°C, and injected pharynx were included in the analysis before non-significant terms were sequentially removed. With 48 tests, the conservative expected number of false discoveries is 2.4.

ISSN: 1471-2334