Table 4 TLR9 haplotypes and severity variables in meningococcal meningitis patients ( p < 0.05)
Severity variable | TLR9 haplotype¹ N (%) | P | OR | 95% | CI | ||||
|---|---|---|---|---|---|---|---|---|---|
I | II | III | IV | Total | |||||
TLR9-1237 | T | T | C | C | 2 N | ||||
TLR9 + 2848 | G | A | A | G | |||||
N. meningitidis in blood culture | |||||||||
Positive | 162 (51)** | 119 (38) | 33 (10) | 2 (1) | 316 | 0.001 | 1.5 | (1.1 2.0) | – |
Negative | 148 (41)** | 147 (41) | 59 (16) | 4 (1) | 358 | ||||
Total | 310 | 266 | 92 | 6 | 674 | ||||
CSF leukocytes per μL | |||||||||
≤ 1000 | 164 (50)* | 122 (38) | 36 (11) | 2 (1) | 324 | 0.03 | 0.7 | (0.5 1.0) | – |
>1000 | 154 (42)* | 144 (40) | 60 (17) | 4 (1) | 362 | ||||
Total | 31 | 266 | 96 | 6 | 686 |