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Table 3 Comparison of rectal inflammation between Intervention and Placebo groups of patients with shigellosis a

From: Efficacy of sodium butyrate adjunct therapy in shigellosis: a randomized, double-blind, placebo-controlled clinical trial

Assessment of Inflammation on day 7 Number of patients improved n (%) compared to day 1 Odds ratiob(95% CI) p valueb Number of patients healed n (%) compared to day 1 Odds ratiob(95% CI) p valueb
Intervention group Placebo group Intervention group Placebo group
By sigmoidoscopy 11 (73.3) 6 (54.5) 2.29 0.324 9 (60) 4 (36) 2.63 0.239
n = 15 n = 11 (0.4-11.9) n = 15 n = 11 (0.5-13.1)
By histology 13 (92.8) 5 (50) 13 0.035 11 (78.6) 1(10) 33 0.005
  n = 14c n = 10c (1.2-140.7)   n = 14c n = 10c (2.9-374.3)  
  1. Abbreviation: CI Confidence interval.
  2. aData are given as number of patients (% of total patients in each group).
  3. bChi-square test was used to compare between groups. Significance: p≤ 0.05.
  4. cOne patient in the Intervention and one in the Placebo group did not have histological feature of inflammation on day 1 and thus excluded from the analysis.