LL-37 level in the stool of
-infected patients, treated with butyrate or placebo. Stool specimens were collected on indicated time points from Intervention (n = 39) or Placebo (n = 37) groups of patients. Level of LL-37 in stool extracts was measured by enzyme linked immunosorbent assay (ELISA). Data are represented as mean ± SEM. Two-way repeated measure ANOVA was performed to determine significant interaction between butyrate and placebo therapy on different days, and when interaction was significant the Holm-Sidak post hoc comparison procedure was used to compare the effects of butyrate therapy on outcome measures. Significance: p≤ 0.05. Concentration of LL-37 decreased significantly from day 1 to days 4 and 7 (< 0.001) in both groups. The decrease was significantly higher in the Placebo group than that in the Intervention group (p <0.001).