Table 1 Demographic and clinical characteristics of patients infected with Clostridium difficile tcdA-positive tcdB-positive (A+B+) strains and with tcdA-negative tcdB-positive (A-B+) strains
From: Clinical and microbiologic characteristics of tcdA-negative variant clostridium difficile infections
A+B+ (n = 105) | A-B+ (n = 22) | p value a | ||
|---|---|---|---|---|
Sex (female) | N (%) | 54 (51.4) | 8 (36.4) | 0.244 |
Age | Mean (SD) | 65.2 (15.10) | 58.5 (19.12) | 0.143 |
Length of hospital stay | Mean (SD) | 34.8 (44.41) | 24.3 (21.20) | 0.583 |
Charlson score | Mean (SD) | 3.17 (2.482) | 2.50 (2.345) | 0.172 |
Underlying disease | ||||
COPD | N (%) | 8 (7.6) | 5 (22.7) | 0.049 |
CVA | N (%) | 28 (26.7) | 2 (9.1) | 0.100 |
Surgical procedure | N (%) | 28 (26.7) | 2 (9.1) | 0.100 |
Severity score | Mean (SD) | 0.96 (0.746) | 1.00 (0.873) | 0.961 |
Old age b | N (%) | 67 (63.8) | 12 (54.5) | 0.472 |
Fever c | N (%) | 10 (9.5) | 5 (22.7) | 0.137 |
Hypoalbuminemia d | N (%) | 10 (9.5) | 1 (4.5) | 0.688 |
Leukocytosis e | N (%) | 14 (13.3) | 4 (18.2) | 0.515 |
Severe CDI f | N (%) | 20 (19.0) | 4 (18.2) | 0.925 |
Clinical findings | ||||
Pain | N (%) | 25 (23.8) | 10 (45.5) | 0.063 |
Tenderness | N (%) | 36 (34.3) | 10 (45.5) | 0.338 |
Stool Fr ≥10/day | N (%) | 21 (20.4) | 2 (9.1) | 0.362 |
Mucoid stool | N (%) | 19 (18.1) | 8 (36.4) | 0.083 |
Laboratory findings | ||||
WBC (cells/mm3) | Mean (SD) | 10892 (5527) | 10263 (7746) | 0.239 |
Albumin (mg/dL) | Mean (SD) | 3.1 (0.57) | 3.4 (0.53) | 0.073 |
CRP (mg/dL) | Mean (SD) | 7.40 (6.397) | 5.98 (6.194) | 0.139 |
Pseudomembrane g | N (%) | 10/26 (38.5) | 2/5 (40.0) | |