Table 3 Patients with positive immunospot test with symptoms suggestive of possible TB, abnormal chest radiograph or positive sputum culture
From: Latent and subclinical tuberculosis in HIV infected patients: a cross-sectional study
Patient | Country of origin | CD4 (cells/ul) | Receiving HAART | Clinical features | Chest radiograph | Sputum culture | Other investigations | Treatment | Final diagnosis |
|---|---|---|---|---|---|---|---|---|---|
1 | Zimbabwe | 413 | Yes | No symptoms | Normal | Positive M. tuberculosis – fully sensitive |  | 2RHEZ, 4RH | Pulmonary TB |
2 | Cameroon | 350 | No | Posterior cervical lymphadenopathy | Normal | None received | FNA cervical lymph node, culture negative | 2RHZ | LTBI |
3 | Turkey | 331 | Yes | Back pain and spinal tenderness | Normal | None received | MRI spine normal | 6H | LTBI |
4 | Burundi | 843 | No | Memory problems; schizoaffective disorder Recent weight loss | Normal | Negative | MRI brain - normal | 6RHZ | Presumed TB (weight increased on treatment) |
5 | Congo | 437 | No | Weight loss 7 kg; anaemia, hypertension | Reported normal, but review suggested Left hilar lymph nodes | Negative | CT scan: 8 mm axillary lymph nodes; ground glass shadowing right paravertebral region | 2RHZ | LTBI |
6* | Jamaica | 539 | No | Paranoid schizophrenia | Large emphysematous bullae | Negative | Inflammatory markers | 6H | LTBI |
7* | Nigeria | 402 | Yes | No symptoms | Blunting of left costophrenic angle | None received | Inflammatory markers | 6H | LTBI |
8 | Kenya | 168 | Yes | No symptoms | Bronchopneumonia 2 months before; now normal chest radiograph | Negative | Inflammatory markers | 6H | LTBI |
9 | Angola | 1372 | Yes | No symptoms; cardiac murmur | Minor left basal shadowing – no evidence of TB | Negative | Inflammatory markers | 6H | LTBI |
10 | Uganda | 980 | Yes | No symptoms | Peribronchial thickening within the right perihilar region | Negative | Other investigations ordered but not received | 6H | Isoniazid-resistant TB 2 years later |
11 | UK | 345 | No | Epilepsy | Left hilum appears bulky | Negative | CXR at 6 months no change | 3RH | LTBI |
12 | Guinea Bissau | 1028 | Yes | Chest pain ? pericarditis | Blunting left costophrenic angle | Negative | Normal echocardiogram | 6H | LTBI |
13 | Nigeria | 414 | Yes | Chronic cough; inguinal lymph nodes (follicular hyperplasia) | Right paratracheal region abnormal and right hilum. Reviewed by radiology team and considered normal | Negative | Inflammatory markers | 6H | LTBI |
14 | Zambia | 829 | Yes | General aches | 2cm lung nodule | Negative | Vitamin D levels low | 6H | LTBI |
15 | Ghana | 122 | Yes | Fevers and sweats for 7 months (previously denied any symptoms) | 1 cm nodule medial to left superior pulmonary vein with blunting left costophrenic angle | PositiveM. tuberculosis isolated – fully sensitive | CT scan – extensive cervical lympadenopathy, left upper zone infiltration and splenomegaly, FNA – TB | 2RHEZ, 4RH | Pulmonary and lymph node TB |