Table 1 Clinical characteristics of patients with benign 3rd and 6th nerve palsy post-immunization
From: Recurrent 6th nerve palsy in a child following different live attenuated vaccines: case report
Authors | Age/Gender/Side of paralysis | Vaccine Type | CN | Time-post Vaccine | Investigations | Outcome |
|---|---|---|---|---|---|---|
Werner et al.[5] | 1 yr 3 mths/F/L | MMR | VI | 10 days | CT Brain | Resolved over 3 months |
0 yr 8 mths/F/L | DPT | VI | 6 weeks | Nil | Resolved over 6 months | |
DPT Booster | VI | 3mths | Nil | Resolved over 2 months | ||
McCormick et al.[7] | 1 yr 1 mth/F/L | MMR | VI | 1 week | FBE, CRP, Anti-Nuclear Antibody (ANA), Measles and mumps serum titers, Anti-Mitochondrial antibody, blood cultures, serum rotavirus titer | Resolved over 8 weeks |
Feces culture for parasites and C difficile | ||||||
CT Brain | ||||||
Leidermann et al.[8] | 1 yr 5 mths/M/R | Influenza | VI | 3 weeks | MRI Brain (T1, T2, Flair) | Initial 10–20 degree incomitant esotropia with limitation of abduction |
12 weeks – 10 degree esotropia in R gaze | ||||||
7 months – residual motility deficit | ||||||
Sturm et al.[3] | 6 mths/M/R | DPT, Polio, Hib | VI | 6 months | MRI Brain | Resolved at 5 days |
Mahoney et al.[9] | 1 yr 8 mths/M/L | DPT, Hib | VI | 3 weeks | MRI, AchRab | Improving but incomplete |
2 yr 7 mths/M/L | VZV | VI | 2.5 weeks | |||
Manzotti et al.[10] | 20mths/M/L | MMR | III | 3 weeks | FBE, UEC | Resolved at 20 days |
CMV, EBV, HSV, | ||||||
VZV, Parvo B19, Influenza, Parainfluenza, RSV titers | ||||||
Electroencephalography, MRI brain | ||||||
Chan et al.[11] | 1 yr 5 mths/M/R | Edmonston Measles | III | 2 weeks | FBE, UEC, ESR, blood sugar level, CSF for protein, glucose, viral, bacterial, Blood cultures, Serum measles titer | Resolved at 2 months |
Skull x-ray, electroencephalography, CT Brain | ||||||
PPD Tuberculin Skin test | ||||||
Intravenous Pyelogram (IVP) | ||||||
Bone marrow aspirate |