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Figure 2 | BMC Infectious Diseases

Figure 2

From: Point-of-care detection of lipoarabinomannan (LAM) in urine for diagnosis of HIV-associated tuberculosis: a state of the art review

Figure 2

Graph showing the sensitivity of a commercially available enzyme-linked immunosorbent assay (ELISA) to detect lipoarabinomannan (LAM) within urine samples to diagnose tuberculosis (TB) in a cohort of patients accessing antiretroviral treatment (ART) in a South African township.

The sensitivity (%) of sputum microscopy and the LAM ELISA are shown individually and combined (either positive) compared with a gold standard of automated liquid culture of two sputum samples. Data are stratified by CD4 cell count (cells/μL) and show that the sensitivity of the LAM ELISA was substantially greater in the patients with the lowest CD4 cell counts. Figure reproduced from Lawn et al. 2011 [5] and data originally from Lawn et al. 2009 [31].

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