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Figure 1 | BMC Infectious Diseases

Figure 1

From: Point-of-care detection of lipoarabinomannan (LAM) in urine for diagnosis of HIV-associated tuberculosis: a state of the art review

Figure 1

Cartoon showing the basic structure of mycobacterial lipoarabinomannan (LAM) and its three main domains.

(i) The glycophospholipid anchor binds the molecule to the plasma membrane of the organism. (ii) The mannan core is attached to this and is highly conserved across mycobacterial species. (iii) The variable branching arabinan side chains and the variable mannose capping of these side chains gives rise to the diversity of LAM molecules.

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