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Table 3 Diagnostic accuracy of TST and QFT-IT in the diagnosis of active TB

From: The clinical utility of tuberculin skin test and interferon-γ release assay in the diagnosis of active tuberculosis among young adults: a prospective observational study

 

TST (n = 142)

QFT-IT (n = 138)

P value

Sensitivity, % (95% CI)

94 (87-98)

93 (86-97)

0.79

Specificity, % (95% CI)

88 (74-96)

95 (81-99)

0.53

PPV, % (95% CI)

95 (88-98)

98 (92-99)

0.47

NPV, % (95% CI)

86 (72-94)

84 (69-93)

0.73

LR+ (95% CI)

8.1 (3.5-18.4)

17.7(4.6-68.2)

 

LR- (95% CI)

0.07 (0.03-0.15)

0.07 (0.04-0.15)

 

AUC (95% CI)

0.91 (0.85-0.97)

0.94 (0.89-0.99)

 
  1. PPV, positive predictive value; NPV, negative predictive value, LR+, positive likelihood ratio; LR-, negative likelihood ratio; AUC, area under curve; TST, tuberculin skin test; QFT-IT, QuantiFERON® TB Gold In-Tube assay
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BMC Infectious Diseases

ISSN: 1471-2334

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