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Table 2 The patterns of gyrA/B mutation and OFX MICs profile of 11 OFX-resistant MTB strains

From: Association of mutation patterns in gyrA/B genes and ofloxacin resistance levels in Mycobacterium tuberculosisisolates from East China in 2009

gyrB

gyrA

No. of strains

Codon mutation

Nucleotide change

Codon mutation

MICs (mg/L)

   

2

4

8

16

G551R

GGG-AGG

A90 V

 

1

1

 

G551R

GGG-AGG

D94G

 

1

  

D500N

GAC-AAC

A90V

   

1

D500N

GAC-AAC

S91P

   

1

D500N

GAC-AAC

D94N

  

1

 

D500N

GAC-AAC

No mutation

  

1

 

T539N

ACC-AAC

A90V

  

2

 

R485L

CGT-CTT

No mutation

1

   

R485C

CGT-TGT

A90V

  

1

 
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BMC Infectious Diseases

ISSN: 1471-2334

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